Untangling Ligand Induced Activation and Desensitization of G-Protein–Coupled Receptors

Por Woolf, Peter J., Linderman, Jennifer J.
Publicado em 2003

Lipid Raft-Mediated Regulation of G-Protein Coupled Receptor Signaling by Ligands which Influence Receptor Dimerization: A Computational Study

Por Fallahi-Sichani, Mohammad, Linderman, Jennifer J.
Publicado em 2009

Mathematical and computational approaches can complement experimental studies of host-pathogen interactions

Por Kirschner, Denise E., Linderman, Jennifer J.
Publicado em 2009

In silico models of M. tuberculosis infection provide a route to new therapies

Por Linderman, Jennifer J., Kirschner, Denise E.
Publicado no Drug Discov Today Dis Models (2014)

Both Ligand- and Cell-Specific Parameters Control Ligand Agonism in a Kinetic Model of G Protein–Coupled Receptor Signaling

Por Kinzer-Ursem, Tamara L, Linderman, Jennifer J
Publicado em 2007

Harnessing the Heterogeneity of T Cell Differentiation Fate to Fine-Tune Generation of Effector and Memory T Cells

Por Gong, Chang, Linderman, Jennifer J., Kirschner, Denise
Publicado em 2014

A POPULATION MODEL CAPTURING DYNAMICS OF TUBERCULOSIS GRANULOMAS PREDICTS HOST INFECTION OUTCOMES

Por Gong, Chang, Linderman, Jennifer J., Kirschner, Denise
Publicado no Math Biosci Eng (2015)

Multiple mechanisms allow Mycobacterium tuberculosis to continuously inhibit MHC class II-mediated antigen presentation by macrophages

Por Chang, Stewart T., Linderman, Jennifer J., Kirschner, Denise E.
Publicado em 2005

Effect of Multiple Genetic Polymorphisms on Antigen Presentation and Susceptibility to Mycobacterium tuberculosis Infection

Por Chang, Stewart T., Linderman, Jennifer J., Kirschner, Denise E.
Publicado em 2008

Diffusion-limited reactions in G-protein activation: Unexpected Consequences of Antagonist and Agonist Competition

Por Brinkerhoff, Christopher J., Choi, Ji Sun, Linderman, Jennifer J.
Publicado em 2008

Collision coupling, crosstalk, and compartmentalization in G-protein coupled receptor systems: Can a single model explain disparate results?

Por Brinkerhoff, Christopher J., Traynor, John R., Linderman, Jennifer J.
Publicado em 2008

NF-κB Signaling Dynamics Play a Key Role in Infection Control in Tuberculosis

Por Fallahi-Sichani, Mohammad, Kirschner, Denise E., Linderman, Jennifer J.
Publicado em 2012

Strategies for efficient numerical implementation of hybrid multi-scale agent-based models to describe biological systems

Por Cilfone, Nicholas A., Kirschner, Denise E., Linderman, Jennifer J.
Publicado no Cell Mol Bioeng (2015)

In silico evaluation and exploration of antibiotic tuberculosis treatment regimens

Por Pienaar, Elsje, Dartois, Véronique, Linderman, Jennifer J., Kirschner, Denise E.
Publicado no BMC Syst Biol (2015)

Strategic Priming with Multiple Antigens can Yield Memory Cell Phenotypes Optimized for Infection with Mycobacterium tuberculosis: A Computational Study

Por Ziraldo, Cordelia, Gong, Chang, Kirschner, Denise E., Linderman, Jennifer J.
Publicado no Front Microbiol (2016)

Ruffles limit diffusion in the plasma membrane during macropinosome formation

Por Welliver, Timothy P., Chang, S. Laura, Linderman, Jennifer J., Swanson, Joel A.
Publicado em 2011

Multi-Scale Modeling Predicts a Balance of Tumor Necrosis Factor-α and Interleukin-10 Controls the Granuloma Environment during Mycobacterium tuberculosis Infection

Por Cilfone, Nicholas A., Perry, Cory R., Kirschner, Denise E., Linderman, Jennifer J.
Publicado em 2013

Systems biology approaches for understanding cellular mechanisms of immunity in lymph nodes during infection

Por Mirsky, Henry Philip, Miller, Mark J., Linderman, Jennifer J., Kirschner, Denise E.
Publicado no J Theor Biol (2011)

Differential risk of tuberculosis reactivation among anti-TNF therapies is due to drug binding kinetics and permeability

Por Fallahi-Sichani, Mohammad, Flynn, JoAnne L., Linderman, Jennifer J., Kirschner, Denise E.
Publicado em 2012

Microfluidic interrogation and mathematical modeling of multi-regime calcium signaling dynamics

Por Jovic, Andreja, Wade, Susan M., Neubig, Richard R., Linderman, Jennifer J., Takayama, Shuichi
Publicado em 2013