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Collision coupling, crosstalk, and compartmentalization in G-protein coupled receptor systems: Can a single model explain disparate results?

The collision coupling model describes interactions between receptors and G-proteins as first requiring the molecules to find each other by diffusion. A variety of experimental data on G-protein activation have been interpreted as suggesting (or not) the compartmentalization of receptors and/or G-pr...

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Detalhes bibliográficos
Main Authors: Brinkerhoff, Christopher J., Traynor, John R., Linderman, Jennifer J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917770/
https://ncbi.nlm.nih.gov/pubmed/18761019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2008.08.003
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