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Ruffles limit diffusion in the plasma membrane during macropinosome formation

In murine macrophages stimulated with macrophage-colony-stimulating factor (M-CSF), signals essential to macropinosome formation are restricted to the domain of plasma membrane enclosed within cup-shaped, circular ruffles. Consistent with a role for these actin-rich structures in signal amplificatio...

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Detalhes bibliográficos
Main Authors: Welliver, Timothy P., Chang, S. Laura, Linderman, Jennifer J., Swanson, Joel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244989/
https://ncbi.nlm.nih.gov/pubmed/22194306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.091538
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