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A growth factor signaling cascade confined to circular ruffles in macrophages

The formation of macropinosomes requires large-scale movements of membranes and the actin cytoskeleton. Over several minutes, actin-rich surface ruffles transform into 1–5 µm diameter circular ruffles, which close at their distal margins, creating endocytic vesicles. Previous studies using fluoresce...

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Bibliografiske detaljer
Main Authors: Welliver, Timothy P., Swanson, Joel A.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507227/
https://ncbi.nlm.nih.gov/pubmed/23213469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20121784
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