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Dorsal ruffles enhance activation of Akt by growth factors
In fibroblasts, platelet-derived growth factor (PDGF) and epidermal growth factor (EGF) stimulate the formation of actin-rich, circular dorsal ruffles (CDRs) and phosphatidylinositol 3-kinase (PI3K)-dependent phosphorylation of Akt. To test the hypothesis that CDRs increase synthesis of phosphorylat...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6262771/ https://ncbi.nlm.nih.gov/pubmed/30333140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.220517 |
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