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Growth factor signaling to mTORC1 by amino acid–laden macropinosomes
The rapid activation of the mechanistic target of rapamycin complex-1 (mTORC1) by growth factors is increased by extracellular amino acids through yet-undefined mechanisms of amino acid transfer into endolysosomes. Because the endocytic process of macropinocytosis concentrates extracellular solutes...
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| 出版年: | J Cell Biol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4602043/ https://ncbi.nlm.nih.gov/pubmed/26438830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201504097 |
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