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Lysosomal Regulation of mTORC1 by Amino Acids in Mammalian Cells
The mechanistic target of rapamycin complex 1 (mTORC1) is a master regulator of cell growth in eukaryotic cells. The active mTORC1 promotes cellular anabolic processes including protein, pyrimidine, and lipid biosynthesis, and inhibits catabolic processes such as autophagy. Consistent with its growt...
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| Publicado no: | Biomolecules |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5618232/ https://ncbi.nlm.nih.gov/pubmed/28686218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom7030051 |
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