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Lipid Raft-Mediated Regulation of G-Protein Coupled Receptor Signaling by Ligands which Influence Receptor Dimerization: A Computational Study

G-protein coupled receptors (GPCRs) are the largest family of cell surface receptors; they activate heterotrimeric G-proteins in response to ligand stimulation. Although many GPCRs have been shown to form homo- and/or heterodimers on the cell membrane, the purpose of this dimerization is not known....

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Bibliografiske detaljer
Main Authors: Fallahi-Sichani, Mohammad, Linderman, Jennifer J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719103/
https://ncbi.nlm.nih.gov/pubmed/19668374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006604
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