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Lipid Raft-Mediated Regulation of G-Protein Coupled Receptor Signaling by Ligands which Influence Receptor Dimerization: A Computational Study

G-protein coupled receptors (GPCRs) are the largest family of cell surface receptors; they activate heterotrimeric G-proteins in response to ligand stimulation. Although many GPCRs have been shown to form homo- and/or heterodimers on the cell membrane, the purpose of this dimerization is not known....

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書目詳細資料
Main Authors: Fallahi-Sichani, Mohammad, Linderman, Jennifer J.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719103/
https://ncbi.nlm.nih.gov/pubmed/19668374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006604
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