Mechanism of Substrate Recognition by Drug-Resistant Human Immunodeficiency Virus Type 1 Protease Variants Revealed by a Novel Structural Intermediate

Por Prabu-Jeyabalan, Moses, Nalivaika, Ellen A., Romano, Keith, Schiffer, Celia A.
Publicado em 2006

Viability of a Drug-Resistant Human Immunodeficiency Virus Type 1 Protease Variant: Structural Insights for Better Antiviral Therapy

Por Prabu-Jeyabalan, Moses, Nalivaika, Ellen A., King, Nancy M., Schiffer, Celia A.
Publicado em 2003

Structural Basis for Coevolution of a Human Immunodeficiency Virus Type 1 Nucleocapsid-p1 Cleavage Site with a V82A Drug-Resistant Mutation in Viral Protease

Por Prabu-Jeyabalan, Moses, Nalivaika, Ellen A., King, Nancy M., Schiffer, Celia A.
Publicado em 2004

Computational design and experimental study of tighter binding peptides to an inactivated mutant of HIV-1 protease

Por Altman, Michael D., Nalivaika, Ellen A., Prabu-Jeyabalan, Moses, Schiffer, Celia A., Tidor, Bruce
Publicado em 2008

Dengue Protease Substrate Recognition: Binding of the Prime Side

Por Lin, Kuan-Hung, Nalivaika, Ellen A., Prachanronarong, Kristina L., Yilmaz, Nese Kurt, Schiffer, Celia A.
Publicado no ACS Infect Dis (2016)

Substrate Envelope and Drug Resistance: Crystal Structure of RO1 in Complex with Wild-Type Human Immunodeficiency Virus Type 1 Protease

Por Prabu-Jeyabalan, Moses, King, Nancy M., Nalivaika, Ellen A., Heilek-Snyder, Gabrielle, Cammack, Nick, Schiffer, Celia A.
Publicado em 2006

Structural and Thermodynamic Basis for the Binding of TMC114, a Next-Generation Human Immunodeficiency Virus Type 1 Protease Inhibitor

Por King, Nancy M., Prabu-Jeyabalan, Moses, Nalivaika, Ellen A., Wigerinck, Piet, de Béthune, Marie-Pierre, Schiffer, Celia A.
Publicado em 2004

The Effect of Clade-Specific Sequence Polymorphisms on HIV-1 Protease Activity and Inhibitor Resistance Pathways

Por Bandaranayake, Rajintha M., Kolli, Madhavi, King, Nancy M., Nalivaika, Ellen A., Heroux, Annie, Kakizawa, Junko, Sugiura, Wataru, Schiffer, Celia A.
Publicado em 2010

Structural and Thermodynamic Basis of Amprenavir/Darunavir and Atazanavir Resistance in HIV-1 Protease with Mutations at Residue 50

Por Mittal, Seema, Bandaranayake, Rajinthna M., King, Nancy M., Prabu-Jeyabalan, Moses, Nalam, Madhavi N. L., Nalivaika, Ellen A., Kurt Yilmaz, Nese, Schiffer, Celia A.
Publicado em 2013

Lack of synergy for inhibitors targeting a multi-drug-resistant HIV-1 protease

Por King, Nancy M., Melnick, Laurence, Prabu-Jeyabalan, Moses, Nalivaika, Ellen A., Yang, Shiow-Shong, Gao, Yun, Nie, Xiaoyi, Zepp, Charles, Heefner, Donald L., Schiffer, Celia A.
Publicado em 2002

Extreme Entropy-Enthalpy Compensation in a Drug Resistant Variant of HIV-1 Protease

Por King, Nancy M., Prabu-Jeyabalan, Moses, Bandaranayake, Rajintha M., Nalam, Madhavi N. L., Nalivaika, Ellen A., Özen, Ayşegül, Haliloglu, Türkan, Yılmaz, Neşe Kurt, Schiffer, Celia A.
Publicado em 2012

Drug Resistance Conferred by Mutations Outside the Active Site through Alterations in the Dynamic and Structural Ensemble of HIV-1 Protease

Por Ragland, Debra A., Nalivaika, Ellen A., Nalam, Madhavi N. L., Prachanronarong, Kristina L., Cao, Hong, Bandaranayake, Rajintha M., Cai, Yufeng, Kurt-Yilmaz, Nese, Schiffer, Celia A.
Publicado em 2014

The ssDNA Mutator APOBEC3A is Regulated by Cooperative Dimerization

Por Bohn, Markus-Frederik, Shandilya, Shivender M.D., Silvas, Tania V., Nalivaika, Ellen A., Kouno, Takahide, Kelch, Brian A., Ryder, Sean P., Kurt-Yilmaz, Nese, Somasundaran, Mohan, Schiffer, Celia A.
Publicado no Structure (2015)

Molecular Basis for Drug Resistance in HIV-1 Protease

Por Ali, Akbar, Bandaranayake, Rajintha M., Cai, Yufeng, King, Nancy M., Kolli, Madhavi, Mittal, Seema, Murzycki, Jennifer F., Nalam, Madhavi N.L., Nalivaika, Ellen A., Özen, Ayşegül, Prabu-Jeyabalan, Moses M., Thayer, Kelly, Schiffer, Celia A.
Publicado em 2010

Crystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfaces

Por Shandilya, Shivender M. D., Nalam, Madhavi N. L., Nalivaika, Ellen A., Gross, Phillip J., Valesano, John C., Shindo, Keisuke, Li, Ming, Munson, Mary, Harjes, Elena, Kouno, Takahide, Matsuo, Hiroshi, Harris, Reuben S., Somasundaran, Mohan, Schiffer, Celia A.
Publicado em 2010