Pharmacokinetics, Safety, and Tolerability of GLPG0259, a Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5) Inhibitor, Given as Single and Multiple Doses to He...

le Namour, Florence, Vanhoutte, Frédéric P., Beetens, Johan, Blockhuys, Stan, Weer, Marc De, Wigerinck, Piet
Foilsithe 2012

Structural and Thermodynamic Basis for the Binding of TMC114, a Next-Generation Human Immunodeficiency Virus Type 1 Protease Inhibitor

le King, Nancy M., Prabu-Jeyabalan, Moses, Nalivaika, Ellen A., Wigerinck, Piet, de Béthune, Marie-Pierre, Schiffer, Celia A.
Foilsithe 2004

TMC114, a Novel Human Immunodeficiency Virus Type 1 Protease Inhibitor Active against Protease Inhibitor-Resistant Viruses, Including a Broad Range of Clinical Isolates

le De Meyer, Sandra, Azijn, Hilde, Surleraux, Dominique, Jochmans, Dirk, Tahri, Abdellah, Pauwels, Rudi, Wigerinck, Piet, de Béthune, Marie-Pierre
Foilsithe 2005

Indolopyridones Inhibit Human Immunodeficiency Virus Reverse Transcriptase with a Novel Mechanism of Action

le Jochmans, Dirk, Deval, Jérôme, Kesteleyn, Bart, Van Marck, Herwig, Bettens, Eva, De Baere, Inky, Dehertogh, Pascale, Ivens, Tania, Van Ginderen, Marcia, Van Schoubroeck, Bertrand, Ehteshami, Maryam, Wigerinck, Piet, Götte, Matthias, Hertogs, Kurt
Foilsithe 2006

In Vitro Activity and Preclinical Profile of TMC435350, a Potent Hepatitis C Virus Protease Inhibitor

le Lin, Tse-I, Lenz, Oliver, Fanning, Gregory, Verbinnen, Thierry, Delouvroy, Frédéric, Scholliers, Annick, Vermeiren, Katrien, Rosenquist, Åsa, Edlund, Michael, Samuelsson, Bertil, Vrang, Lotta, de Kock, Herman, Wigerinck, Piet, Raboisson, Pierre, Simmen, Kenneth
Foilsithe 2009