Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Stereopure Lactam-Based HIV-1 Protease Inhibitors

Por Wu, Xiongyu, Öhrngren, Per, Joshi, Advait A., Trejos, Alejandro, Persson, Magnus, Arvela, Riina K., Wallberg, Hans, Vrang, Lotta, Rosenquist, Åsa, Samuelsson, Bertil B., Unge, Johan, Larhed, Mats
Publicado em 2012

In Vitro Activity and Preclinical Profile of TMC435350, a Potent Hepatitis C Virus Protease Inhibitor

Por Lin, Tse-I, Lenz, Oliver, Fanning, Gregory, Verbinnen, Thierry, Delouvroy, Frédéric, Scholliers, Annick, Vermeiren, Katrien, Rosenquist, Åsa, Edlund, Michael, Samuelsson, Bertil, Vrang, Lotta, de Kock, Herman, Wigerinck, Piet, Raboisson, Pierre, Simmen, Kenneth
Publicado em 2009

Preclinical Evaluation of 1H-Benzylindole Derivatives as Novel Human Immunodeficiency Virus Integrase Strand Transfer Inhibitors

Por Hombrouck, Anneleen, Van Remoortel, Barbara, Michiels, Martine, Noppe, Wim, Christ, Frauke, Eneroth, Anders, Sahlberg, Britt Louise, Benkestock, Kurt, Vrang, Lotta, Johansson, Nils Gunnar, Barreca, Maria Letizia, De Luca, Laura, Ferro, Stefania, Chimirri, Alba, Debyser, Zeger, Witvrouw, Myriam
Publicado em 2008

In Vitro Resistance Profile of the Hepatitis C Virus NS3/4A Protease Inhibitor TMC435

Por Lenz, Oliver, Verbinnen, Thierry, Lin, Tse-I, Vijgen, Leen, Cummings, Maxwell D., Lindberg, Jimmy, Berke, Jan Martin, Dehertogh, Pascale, Fransen, Els, Scholliers, Annick, Vermeiren, Katrien, Ivens, Tania, Raboisson, Pierre, Edlund, Michael, Storm, Susan, Vrang, Lotta, de Kock, Herman, Fanning, Gregory C., Simmen, Kenneth A.
Publicado em 2010