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In Vitro Resistance Profile of the Hepatitis C Virus NS3/4A Protease Inhibitor TMC435
TMC435 is a small-molecule inhibitor of the NS3/4A serine protease of hepatitis C virus (HCV) currently in phase 2 development. The in vitro resistance profile of TMC435 was characterized by selection experiments with HCV genotype 1 replicon cells and the genotype 2a JFH-1 system. In 80% (86/109) of...
Tallennettuna:
| Päätekijät: | , , , , , , , , , , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Microbiology (ASM)
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863659/ https://ncbi.nlm.nih.gov/pubmed/20176898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01452-09 |
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