TMC647055, a Potent Nonnucleoside Hepatitis C Virus NS5B Polymerase Inhibitor with Cross-Genotypic Coverage

Hepatitis C virus (HCV) infection is a major global health burden and is associated with an increased risk of liver cirrhosis and hepatocellular carcinoma. There remains an unmet medical need for efficacious and safe direct antivirals with complementary modes of action for combination in treatment r...

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Detalhes bibliográficos
Main Authors: Devogelaere, Benoit, Berke, Jan Martin, Vijgen, Leen, Dehertogh, Pascale, Fransen, Els, Cleiren, Erna, van der Helm, Liesbet, Nyanguile, Origène, Tahri, Abdellah, Amssoms, Katie, Lenz, Oliver, Cummings, Maxwell D., Clayton, Reginald F., Vendeville, Sandrine, Raboisson, Pierre, Simmen, Kenneth A., Fanning, Gregory C., Lin, Tse-I
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421868/
https://ncbi.nlm.nih.gov/pubmed/22710121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00245-12
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