1a/1b Subtype Profiling of Nonnucleoside Polymerase Inhibitors of Hepatitis C Virus

The RNA-dependent RNA polymerase (NS5B) of hepatitis C virus (HCV) is an unusually attractive target for drug discovery since it contains five distinct drugable sites. The success of novel antiviral therapies will require nonnucleoside inhibitors to be active in at least patients infected with HCV o...

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Hauptverfasser: Nyanguile, Origène, Devogelaere, Benoit, Vijgen, Leen, Van den Broeck, Walter, Pauwels, Frederik, Cummings, Maxwell D., De Bondt, Hendrik L., Vos, Ann M., Berke, Jan M., Lenz, Oliver, Vandercruyssen, Geneviève, Vermeiren, Katrien, Mostmans, Wendy, Dehertogh, Pascale, Delouvroy, Frédéric, Vendeville, Sandrine, VanDyck, Koen, Dockx, Koen, Cleiren, Erna, Raboisson, Pierre, Simmen, Kenneth A., Fanning, Gregory C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826027/
https://ncbi.nlm.nih.gov/pubmed/20071590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01980-09
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