1a/1b Subtype Profiling of Nonnucleoside Polymerase Inhibitors of Hepatitis C Virus

The RNA-dependent RNA polymerase (NS5B) of hepatitis C virus (HCV) is an unusually attractive target for drug discovery since it contains five distinct drugable sites. The success of novel antiviral therapies will require nonnucleoside inhibitors to be active in at least patients infected with HCV o...

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Detalhes bibliográficos
Main Authors: Nyanguile, Origène, Devogelaere, Benoit, Vijgen, Leen, Van den Broeck, Walter, Pauwels, Frederik, Cummings, Maxwell D., De Bondt, Hendrik L., Vos, Ann M., Berke, Jan M., Lenz, Oliver, Vandercruyssen, Geneviève, Vermeiren, Katrien, Mostmans, Wendy, Dehertogh, Pascale, Delouvroy, Frédéric, Vendeville, Sandrine, VanDyck, Koen, Dockx, Koen, Cleiren, Erna, Raboisson, Pierre, Simmen, Kenneth A., Fanning, Gregory C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826027/
https://ncbi.nlm.nih.gov/pubmed/20071590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01980-09
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