Capsid Assembly Modulators Have a Dual Mechanism of Action in Primary Human Hepatocytes Infected with Hepatitis B Virus

Hepatitis B virus (HBV) capsid assembly is a critical step in the propagation of the virus and is mediated by the core protein. Due to its multiple functions in the viral life cycle, core became an attractive target for new antiviral therapies. Capsid assembly modulators (CAMs) accelerate the kineti...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Berke, Jan Martin, Dehertogh, Pascale, Vergauwen, Karen, Van Damme, Ellen, Mostmans, Wendy, Vandyck, Koen, Pauwels, Frederik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527576/
https://ncbi.nlm.nih.gov/pubmed/28584155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00560-17
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