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Novel Potent Capsid Assembly Modulators Regulate Multiple Steps of the Hepatitis B Virus Life Cycle

The assembly of hepatitis B virus (HBV) core protein (HBc) into capsids represents a critical step of viral replication. HBc has multiple functions during the HBV life cycle, which makes it an attractive target for antiviral therapies. Capsid assembly modulators (CAMs) induce the formation of empty...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Lahlali, Thomas, Berke, Jan Martin, Vergauwen, Karen, Foca, Adrien, Vandyck, Koen, Pauwels, Frederik, Zoulim, Fabien, Durantel, David
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153789/
https://ncbi.nlm.nih.gov/pubmed/30012770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00835-18
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