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Novel Potent Capsid Assembly Modulators Regulate Multiple Steps of the Hepatitis B Virus Life Cycle

The assembly of hepatitis B virus (HBV) core protein (HBc) into capsids represents a critical step of viral replication. HBc has multiple functions during the HBV life cycle, which makes it an attractive target for antiviral therapies. Capsid assembly modulators (CAMs) induce the formation of empty...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Lahlali, Thomas, Berke, Jan Martin, Vergauwen, Karen, Foca, Adrien, Vandyck, Koen, Pauwels, Frederik, Zoulim, Fabien, Durantel, David
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153789/
https://ncbi.nlm.nih.gov/pubmed/30012770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00835-18
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