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Novel Hepatitis B Virus Capsid Assembly Modulator Induces Potent Antiviral Responses In Vitro and in Humanized Mice

Hepatitis B virus (HBV) affects an estimated 250 million chronic carriers worldwide. Though several vaccines exist, they are ineffective for those already infected. HBV persists due to the formation of covalently closed circular DNA (cccDNA)—the viral minichromosome—in the nucleus of hepatocytes. Cu...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Amblard, Franck, Boucle, Sebastien, Bassit, Leda, Cox, Bryan, Sari, Ozkan, Tao, Sijia, Chen, Zhe, Ozturk, Tugba, Verma, Kiran, Russell, Olivia, Rat, Virgile, de Rocquigny, Hugues, Fiquet, Oriane, Boussand, Maud, Di Santo, James, Strick-Marchand, Helene, Schinazi, Raymond F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985704/
https://ncbi.nlm.nih.gov/pubmed/31712213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01701-19
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