Novel Hepatitis B Virus Capsid Assembly Modulator Induces Potent Antiviral Responses In Vitro and in Humanized Mice

Hepatitis B virus (HBV) affects an estimated 250 million chronic carriers worldwide. Though several vaccines exist, they are ineffective for those already infected. HBV persists due to the formation of covalently closed circular DNA (cccDNA)—the viral minichromosome—in the nucleus of hepatocytes. Cu...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Antimicrob Agents Chemother
Main Authors: Amblard, Franck, Boucle, Sebastien, Bassit, Leda, Cox, Bryan, Sari, Ozkan, Tao, Sijia, Chen, Zhe, Ozturk, Tugba, Verma, Kiran, Russell, Olivia, Rat, Virgile, de Rocquigny, Hugues, Fiquet, Oriane, Boussand, Maud, Di Santo, James, Strick-Marchand, Helene, Schinazi, Raymond F.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2020
נושאים:
Antiviral Agents
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985704/
https://ncbi.nlm.nih.gov/pubmed/31712213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01701-19
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