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Discovery and Structure Activity Relationship of Glyoxamide Derivatives as Anti-Hepatitis B Virus Agents

Chronic hepatitis B viral infection is a significant health problem world-wide, and currently available antiviral agents suppress HBV infections, but rarely cure this disease. It is presumed that antiviral agents that target the viral nuclear reservoir of transcriptionally active cccDNA may eliminat...

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Bibliografiske detaljer
Udgivet i:Bioorg Med Chem
Main Authors: Amblard, Franck, Boucle, Sebastien, Bassit, Leda, Chen, Zhe, Sari, Ozkan, Cox, Bryan, Verma, Kiran, Ozturk, Tugba, Ollinger-Russell, Olivia, Schinazi, Raymond F.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856252/
https://ncbi.nlm.nih.gov/pubmed/33421915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2020.115952
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