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Discovery and Structure Activity Relationship of Glyoxamide Derivatives as Anti-Hepatitis B Virus Agents

Chronic hepatitis B viral infection is a significant health problem world-wide, and currently available antiviral agents suppress HBV infections, but rarely cure this disease. It is presumed that antiviral agents that target the viral nuclear reservoir of transcriptionally active cccDNA may eliminat...

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Dettagli Bibliografici
Pubblicato in:Bioorg Med Chem
Autori principali: Amblard, Franck, Boucle, Sebastien, Bassit, Leda, Chen, Zhe, Sari, Ozkan, Cox, Bryan, Verma, Kiran, Ozturk, Tugba, Ollinger-Russell, Olivia, Schinazi, Raymond F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856252/
https://ncbi.nlm.nih.gov/pubmed/33421915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2020.115952
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