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Discovery and Structure Activity Relationship of Glyoxamide Derivatives as Anti-Hepatitis B Virus Agents

Chronic hepatitis B viral infection is a significant health problem world-wide, and currently available antiviral agents suppress HBV infections, but rarely cure this disease. It is presumed that antiviral agents that target the viral nuclear reservoir of transcriptionally active cccDNA may eliminat...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Amblard, Franck, Boucle, Sebastien, Bassit, Leda, Chen, Zhe, Sari, Ozkan, Cox, Bryan, Verma, Kiran, Ozturk, Tugba, Ollinger-Russell, Olivia, Schinazi, Raymond F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856252/
https://ncbi.nlm.nih.gov/pubmed/33421915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2020.115952
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