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Discovery and Structure Activity Relationship of Glyoxamide Derivatives as Anti-Hepatitis B Virus Agents

Chronic hepatitis B viral infection is a significant health problem world-wide, and currently available antiviral agents suppress HBV infections, but rarely cure this disease. It is presumed that antiviral agents that target the viral nuclear reservoir of transcriptionally active cccDNA may eliminat...

詳細記述

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書誌詳細
出版年:Bioorg Med Chem
主要な著者: Amblard, Franck, Boucle, Sebastien, Bassit, Leda, Chen, Zhe, Sari, Ozkan, Cox, Bryan, Verma, Kiran, Ozturk, Tugba, Ollinger-Russell, Olivia, Schinazi, Raymond F.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856252/
https://ncbi.nlm.nih.gov/pubmed/33421915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2020.115952
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