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Discovery and Structure Activity Relationship of Glyoxamide Derivatives as Anti-Hepatitis B Virus Agents

Chronic hepatitis B viral infection is a significant health problem world-wide, and currently available antiviral agents suppress HBV infections, but rarely cure this disease. It is presumed that antiviral agents that target the viral nuclear reservoir of transcriptionally active cccDNA may eliminat...

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Bibliografische gegevens
Gepubliceerd in:Bioorg Med Chem
Hoofdauteurs: Amblard, Franck, Boucle, Sebastien, Bassit, Leda, Chen, Zhe, Sari, Ozkan, Cox, Bryan, Verma, Kiran, Ozturk, Tugba, Ollinger-Russell, Olivia, Schinazi, Raymond F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856252/
https://ncbi.nlm.nih.gov/pubmed/33421915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2020.115952
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