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Novel Potent Capsid Assembly Modulators Regulate Multiple Steps of the Hepatitis B Virus Life Cycle

The assembly of hepatitis B virus (HBV) core protein (HBc) into capsids represents a critical step of viral replication. HBc has multiple functions during the HBV life cycle, which makes it an attractive target for antiviral therapies. Capsid assembly modulators (CAMs) induce the formation of empty...

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Bibliografiset tiedot
Julkaisussa:Antimicrob Agents Chemother
Päätekijät: Lahlali, Thomas, Berke, Jan Martin, Vergauwen, Karen, Foca, Adrien, Vandyck, Koen, Pauwels, Frederik, Zoulim, Fabien, Durantel, David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153789/
https://ncbi.nlm.nih.gov/pubmed/30012770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00835-18
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