TMC647055, a Potent Nonnucleoside Hepatitis C Virus NS5B Polymerase Inhibitor with Cross-Genotypic Coverage

Hepatitis C virus (HCV) infection is a major global health burden and is associated with an increased risk of liver cirrhosis and hepatocellular carcinoma. There remains an unmet medical need for efficacious and safe direct antivirals with complementary modes of action for combination in treatment r...

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Bibliografische gegevens
Hoofdauteurs: Devogelaere, Benoit, Berke, Jan Martin, Vijgen, Leen, Dehertogh, Pascale, Fransen, Els, Cleiren, Erna, van der Helm, Liesbet, Nyanguile, Origène, Tahri, Abdellah, Amssoms, Katie, Lenz, Oliver, Cummings, Maxwell D., Clayton, Reginald F., Vendeville, Sandrine, Raboisson, Pierre, Simmen, Kenneth A., Fanning, Gregory C., Lin, Tse-I
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2012
Onderwerpen:
Antiviral Agents
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421868/
https://ncbi.nlm.nih.gov/pubmed/22710121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00245-12
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