Towards a Functional Cure of HIV-1: Insight Into the Chromatin Landscape of the Provirus

بواسطة Janssens, Julie, Bruggemans, Anne, Christ, Frauke, Debyser, Zeger
الحاوية / القاعدة Front Microbiol (2021)

Insight into HIV-2 latency may disclose strategies for a cure for HIV-1 infection

بواسطة Saleh, Suha, Vranckx, Lenard, Gijsbers, Rik, Christ, Frauke, Debyser, Zeger
الحاوية / القاعدة J Virus Erad (2017)

Insight in HIV Integration Site Selection Provides a Block-and-Lock Strategy for a Functional Cure of HIV Infection

بواسطة Debyser, Zeger, Vansant, Gerlinde, Bruggemans, Anne, Janssens, Julie, Christ, Frauke
الحاوية / القاعدة Viruses (2018)

Synthesis and Anti-HIV Profile of a Novel Tetrahydroindazolylbenzamide Derivative Obtained by Oxazolone Chemistry

بواسطة Scala, Angela, Piperno, Anna, Micale, Nicola, Christ, Frauke, Debyser, Zeger
الحاوية / القاعدة ACS Med Chem Lett (2018)

Cellular Cofactors of Lentiviral Integrase: From Target Validation to Drug Discovery

بواسطة Taltynov, Oliver, Desimmie, Belete A., Demeulemeester, Jonas, Christ, Frauke, Debyser, Zeger
منشور في 2012

Discovery of novel inhibitors of LEDGF/p75-IN protein-protein interactions

بواسطة Sanchez, Tino Wilson, Debnath, Bikash, Christ, Frauke, Otake, Hiroyuki, Debyser, Zeger, Neamati, Nouri
الحاوية / القاعدة Bioorg Med Chem (2012)

Role of Transportin-SR2 in HIV-1 Nuclear Import

بواسطة Tabasi, Maryam, Nombela, Ivan, Janssens, Julie, Lahousse, Adrien P., Christ, Frauke, Debyser, Zeger
الحاوية / القاعدة Viruses (2021)

Fragment-Based Discovery of 8-Hydroxyquinoline Inhibitors of the HIV-1 Integrase-LEDGF/p75 Interaction

بواسطة Serrao, Erik, Debnath, Bikash, Otake, Hiroyuki, Kuang, Yuting, Christ, Frauke, Debyser, Zeger, Neamati, Nouri
الحاوية / القاعدة J Med Chem (2013)

Identification of Residues in the C-terminal Domain of HIV-1 Integrase That Mediate Binding to the Transportin-SR2 Protein

بواسطة De Houwer, Stephanie, Demeulemeester, Jonas, Thys, Wannes, Taltynov, Oliver, Zmajkovicova, Katarina, Christ, Frauke, Debyser, Zeger
منشور في 2012

Structure of transportin SR2, a karyopherin involved in human disease, in complex with Ran

بواسطة Tsirkone, Vicky G., Beutels, Katrien G., Demeulemeester, Jonas, Debyser, Zeger, Christ, Frauke, Strelkov, Sergei V.
منشور في 2014

GS-9822, a Preclinical LEDGIN Candidate, Displays a Block-and-Lock Phenotype in Cell Culture

بواسطة Bruggemans, Anne, Vansant, Gerlinde, Balakrishnan, Mini, Mitchell, Michael L., Cai, Ruby, Christ, Frauke, Debyser, Zeger
الحاوية / القاعدة Antimicrob Agents Chemother (2021)

A Symmetric Region of the HIV-1 Integrase Dimerization Interface Is Essential for Viral Replication

بواسطة Serrao, Erik, Thys, Wannes, Demeulemeester, Jonas, Al-Mawsawi, Laith Q., Christ, Frauke, Debyser, Zeger, Neamati, Nouri
منشور في 2012

Single-Cell Imaging of HIV-1 Provirus (SCIP)

بواسطة Di Primio, Cristina, Quercioli, Valentina, Allouch, Awatef, Gijsbers, Rik, Christ, Frauke, Debyser, Zeger, Arosio, Daniele, Cereseto, Anna
منشور في 2013

The HIV-1 Integrase Mutant R263A/K264A Is 2-fold Defective for TRN-SR2 Binding and Viral Nuclear Import

بواسطة De Houwer, Stéphanie, Demeulemeester, Jonas, Thys, Wannes, Rocha, Susana, Dirix, Lieve, Gijsbers, Rik, Christ, Frauke, Debyser, Zeger
منشور في 2014

Design of a novel cyclotide-based CXCR4 antagonist with anti-human immunodeficiency virus (HIV)-1 activity

بواسطة Aboye, Teshome L., Ha, Helen, Majumber, Subhabrata, Christ, Frauke, Debyser, Zeger, Shekhtman, Alexander, Neamati, Nouri, Camarero, Julio A.
منشور في 2012

Overexpression of the Lens Epithelium-Derived Growth Factor/p75 Integrase Binding Domain Inhibits Human Immunodeficiency Virus Replication

بواسطة De Rijck, Jan, Vandekerckhove, Linos, Gijsbers, Rik, Hombrouck, Anneleen, Hendrix, Jelle, Vercammen, Jo, Engelborghs, Yves, Christ, Frauke, Debyser, Zeger
منشور في 2006

Inhibitors of the integrase–transportin-SR2 interaction block HIV nuclear import

بواسطة Demeulemeester, Jonas, Blokken, Jolien, De Houwer, Stéphanie, Dirix, Lieve, Klaassen, Hugo, Marchand, Arnaud, Chaltin, Patrick, Christ, Frauke, Debyser, Zeger
الحاوية / القاعدة Retrovirology (2018)

Transient and Stable Knockdown of the Integrase Cofactor LEDGF/p75 Reveals Its Role in the Replication Cycle of Human Immunodeficiency Virus

بواسطة Vandekerckhove, Linos, Christ, Frauke, Van Maele, Bénédicte, De Rijck, Jan, Gijsbers, Rik, Van den Haute, Chris, Witvrouw, Myriam, Debyser, Zeger
منشور في 2006

Lens Epithelium-derived Growth Factor/p75 Interacts with the Transposase-derived DDE Domain of PogZ

بواسطة Bartholomeeusen, Koen, Christ, Frauke, Hendrix, Jelle, Rain, Jean-Christophe, Emiliani, Stéphane, Benarous, Richard, Debyser, Zeger, Gijsbers, Rik, De Rijck, Jan
منشور في 2009

2-Hydroxyisoquinoline-1,3(2H, 4H)diones (HQDs), novel inhibitors of the HIV integrase catalytic activity with a high barrier to resistance

بواسطة Christ, Frauke, Demeulemeester, Jonas, Desimmie, Belete, Suchaud, Virginie, Taltynov, Oliver, Lion, Cedric, Bailly, Fabrice, Strelkov, Sergei, Cotelle, Philipe, Debyser, Zeger
منشور في 2013