Lens Epithelium-derived Growth Factor/p75 Interacts with the Transposase-derived DDE Domain of PogZ

Lens epithelium-derived growth factor/p75 (LEDGF/p75) is a prominent cellular interaction partner of human immunodeficiency virus-1 (HIV-1) integrase, tethering the preintegration complex to the host chromosome. In light of the development of LEDGF/p75-integrase interaction inhibitors, it is essenti...

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Autors principals: Bartholomeeusen, Koen, Christ, Frauke, Hendrix, Jelle, Rain, Jean-Christophe, Emiliani, Stéphane, Benarous, Richard, Debyser, Zeger, Gijsbers, Rik, De Rijck, Jan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Molecular Basis of Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670152/
https://ncbi.nlm.nih.gov/pubmed/19244240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807781200
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