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Structure of transportin SR2, a karyopherin involved in human disease, in complex with Ran

Transportin SR2 (TRN-SR2) is a β-type karyopherin responsible for the nuclear import of specific cargoes, including serine/arginine-rich splicing factors. The protein has been implicated in a variety of human diseases, including HIV infection, primary biliary cirrhosis and limb-girdle muscular dystr...

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Detalhes bibliográficos
Main Authors: Tsirkone, Vicky G., Beutels, Katrien G., Demeulemeester, Jonas, Debyser, Zeger, Christ, Frauke, Strelkov, Sergei V.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051523/
https://ncbi.nlm.nih.gov/pubmed/24915079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14009492
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