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Identification of Residues in the C-terminal Domain of HIV-1 Integrase That Mediate Binding to the Transportin-SR2 Protein

Transportin-SR2 (TRN-SR2 and TNPO3) is a cellular cofactor of HIV replication that has been implicated in the nuclear import of HIV. TRN-SR2 was originally identified in a yeast two-hybrid screen as an interaction partner of HIV integrase (IN) and in two independent siRNA screens as a cofactor of vi...

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Bibliografiske detaljer
Main Authors: De Houwer, Stephanie, Demeulemeester, Jonas, Thys, Wannes, Taltynov, Oliver, Zmajkovicova, Katarina, Christ, Frauke, Debyser, Zeger
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464515/
https://ncbi.nlm.nih.gov/pubmed/22872638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.387944
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