Cellular Cofactors of Lentiviral Integrase: From Target Validation to Drug Discovery

To accomplish their life cycle, lentiviruses make use of host proteins, the so-called cellular cofactors. Interactions between host cell and viral proteins during early stages of lentiviral infection provide attractive new antiviral targets. The insertion of lentiviral cDNA in a host cell chromosome...

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Bibliographic Details
Main Authors: Taltynov, Oliver, Desimmie, Belete A., Demeulemeester, Jonas, Christ, Frauke, Debyser, Zeger
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2012
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420096/
https://ncbi.nlm.nih.gov/pubmed/22928108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/863405
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