A carregar...
Extreme Entropy-Enthalpy Compensation in a Drug Resistant Variant of HIV-1 Protease
The development of HIV-1 protease inhibitors has been the historic paradigm of rational structure-based drug design, where structural and thermodynamic analyses have assisted in the discovery of novel inhibitors. While the total enthalpy and entropy change upon binding determine the affinity, often...
Na minha lista:
| Main Authors: | , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594831/ https://ncbi.nlm.nih.gov/pubmed/22712830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300191k |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|