Methodology for the analysis of rare genetic variation in genome-wide association and re-sequencing studies of complex human traits

by Moutsianas, Loukas, Morris, Andrew P.
Published 2014

Approximate Bayesian feature selection on a large meta-dataset offers novel insights on factors that effect siRNA potency

by Klingelhoefer, Jochen W., Moutsianas, Loukas, Holmes, Chris
Published 2009

HLA*IMP—an integrated framework for imputing classical HLA alleles from SNP genotypes

by Dilthey, Alexander T., Moutsianas, Loukas, Leslie, Stephen, McVean, Gil
Published 2011

Multi-Population Classical HLA Type Imputation

by Dilthey, Alexander, Leslie, Stephen, Moutsianas, Loukas, Shen, Judong, Cox, Charles, Nelson, Matthew R., McVean, Gil
Published 2013

Founder population-specific HapMap panel increases power in GWA studies through improved imputation accuracy and CNV tagging

by Surakka, Ida, Kristiansson, Kati, Anttila, Verneri, Inouye, Michael, Barnes, Chris, Moutsianas, Loukas, Salomaa, Veikko, Daly, Mark, Palotie, Aarno, Peltonen, Leena, Ripatti, Samuli
Published 2010

Assessing association between protein truncating variants and quantitative traits

by Rivas, Manuel A., Pirinen, Matti, Neville, Matthew J., Gaulton, Kyle J., Moutsianas, Loukas, Lindgren, Cecilia M., Karpe, Fredrik, McCarthy, Mark I., Donnelly, Peter
Published 2013

Revisiting the Thrifty Gene Hypothesis via 65 Loci Associated with Susceptibility to Type 2 Diabetes

by Ayub, Qasim, Moutsianas, Loukas, Chen, Yuan, Panoutsopoulou, Kalliope, Colonna, Vincenza, Pagani, Luca, Prokopenko, Inga, Ritchie, Graham R.S., Tyler-Smith, Chris, McCarthy, Mark I., Zeggini, Eleftheria, Xue, Yali
Published 2014

The Power of Gene-Based Rare Variant Methods to Detect Disease-Associated Variation and Test Hypotheses About Complex Disease

by Moutsianas, Loukas, Agarwala, Vineeta, Fuchsberger, Christian, Flannick, Jason, Rivas, Manuel A., Gaulton, Kyle J., Albers, Patrick K., McVean, Gil, Boehnke, Michael, Altshuler, David, McCarthy, Mark I.
Published in PLoS Genet (2015)

Hypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways

by Valli, Alessandro, Rodriguez, Miguel, Moutsianas, Loukas, Fischer, Roman, Fedele, Vita, Huang, Hong-Lei, Van Stiphout, Ruud, Jones, Dylan, Mccarthy, Michael, Vinaxia, Maria, Igarashi, Kaori, Sato, Maya, Soga, Tomoyoshi, Buffa, Francesca, Mccullagh, James, Yanes, Oscar, Harris, Adrian, Kessler, Benedikt
Published in Oncotarget (2014)

A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates

by Tachmazidou, Ioanna, Dedoussis, George, Southam, Lorraine, Farmaki, Aliki-Eleni, Ritchie, Graham R. S., Xifara, Dionysia K., Matchan, Angela, Hatzikotoulas, Konstantinos, Rayner, Nigel W., Chen, Yuan, Pollin, Toni I., O’Connell, Jeffrey R., Yerges-Armstrong, Laura M., Kiagiadaki, Chrysoula, Panoutsopoulou, Kalliope, Schwartzentruber, Jeremy, Moutsianas, Loukas, Tsafantakis, Emmanouil, Tyler-Smith, Chris, McVean, Gil, Xue, Yali, Zeggini, Eleftheria
Published 2013

Exploring the genetic architecture of inflammatory bowel disease by whole genome sequencing identifies association at ADCY7

by Luo, Yang, de Lange, Katrina M., Jostins, Luke, Moutsianas, Loukas, Randall, Joshua, Kennedy, Nicholas A., Lamb, Christopher A., McCarthy, Shane, Ahmad, Tariq, Edwards, Cathryn, Serra, Eva Goncalves, Hart, Ailsa, Hawkey, Chris, Mansfield, John C., Mowat, Craig, Newman, William G., Nichols, Sam, Pollard, Martin, Satsangi, Jack, Simmons, Alison, Tremelling, Mark, Uhlig, Holm, Wilson, David C., Lee, James C., Prescott, Natalie J., Lees, Charlie W., Mathew, Christopher G., Parkes, Miles, Barrett, Jeffrey C., Anderson, Carl A.
Published in Nat Genet (2017)

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

by de Lange, Katrina M., Moutsianas, Loukas, Lee, James C., Lamb, Christopher A., Luo, Yang, Kennedy, Nicholas A., Jostins, Luke, Rice, Daniel L., Gutierrez-Achury, Javier, Ji, Sun-Gou, Heap, Graham, Nimmo, Elaine R., Edwards, Cathryn, Henderson, Paul, Mowat, Craig, Sanderson, Jeremy, Satsangi, Jack, Simmons, Alison, Wilson, David C., Tremelling, Mark, Hart, Ailsa, Mathew, Christopher G., Newman, William G., Parkes, Miles, Lees, Charlie W., Uhlig, Holm, Hawkey, Chris, Prescott, Natalie J., Ahmad, Tariq, Mansfield, John C., Anderson, Carl A., Barrett, Jeffrey C.
Published in Nat Genet (2017)

Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease

by Serra, Eva Gonçalves, Schwerd, Tobias, Moutsianas, Loukas, Cavounidis, Athena, Fachal, Laura, Pandey, Sumeet, Kammermeier, Jochen, Croft, Nicholas M., Posovszky, Carsten, Rodrigues, Astor, Russell, Richard K., Barakat, Farah, Auth, Marcus K. H., Heuschkel, Robert, Zilbauer, Matthias, Fyderek, Krzysztof, Braegger, Christian, Travis, Simon P., Satsangi, Jack, Parkes, Miles, Thapar, Nikhil, Ferry, Helen, Matte, Julie C., Gilmour, Kimberly C., Wedrychowicz, Andrzej, Sullivan, Peter, Moore, Carmel, Sambrook, Jennifer, Ouwehand, Willem, Roberts, David, Danesh, John, Baeumler, Toni A., Fulga, Tudor A., Carrami, Eli M., Ahmed, Ahmed, Wilson, Rachel, Barrett, Jeffrey C., Elkadri, Abdul, Griffiths, Anne M., Snapper, Scott B., Shah, Neil, Muise, Aleixo M., Wilson, David C., Uhlig, Holm H., Anderson, Carl A.
Published in Nat Commun (2020)

Class II HLA interactions modulate genetic risk for multiple sclerosis

by Moutsianas, Loukas, Jostins, Luke, Beecham, Ashley H, Dilthey, Alexander T, Xifara, Dionysia K, Ban, Maria, Shah, Tejas S, Patsopoulos, Nikolaos A, Alfredsson, Lars, Anderson, Carl A, Attfield, Katherine E, Baranzini, Sergio E, Barrett, Jeffrey, Binder, Thomas M C, Booth, David, Buck, Dorothea, Celius, Elisabeth G, Cotsapas, Chris, D’Alfonso, Sandra, Dendrou, Calliope A, Donnelly, Peter, Dubois, Bénédicte, Fontaine, Bertrand, Fugger, Lars, Goris, An, Gourraud, Pierre-Antoine, Graetz, Christiane, Hemmer, Bernhard, Hillert, Jan, Kockum, Ingrid, Leslie, Stephen, Lill, Christina M, Martinelli-Boneschi, Filippo, Oksenberg, Jorge R, Olsson, Tomas, Oturai, Annette, Saarela, Janna, Søndergaard, Helle Bach, Spurkland, Anne, Taylor, Bruce, Winkelmann, Juliane, Zipp, Frauke, Haines, Jonathan L, Pericak-Vance, Margaret A, Spencer, Chris C A, Stewart, Graeme, Hafler, David A, Ivinson, Adrian J, Harbo, Hanne F, Hauser, Stephen L, De Jager, Philip L, Compston, Alastair, McCauley, Jacob L, Sawcer, Stephen, McVean, Gil
Published in Nat Genet (2015)

Genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1

by Strange, Amy, Capon, Francesca, Spencer, Chris CA, Knight, Jo, Weale, Michael E, Allen, Michael H, Barton, Anne, Band, Gavin, Bellenguez, Céline, Bergboer, Judith GM, Blackwell, Jenefer M, Bramon, Elvira, Bumpstead, Suzannah J, Casas, Juan P, Cork, Michael J, Corvin, Aiden, Deloukas, Panos, Dilthey, Alexander, Duncanson, Audrey, Edkins, Sarah, Estivill, Xavier, Fitzgerald, Oliver, Freeman, Colin, Giardina, Emiliano, Gray, Emma, Hofer, Angelika, Hüffmeier, Ulrike, Hunt, Sarah E, Irvine, Alan D, Jankowski, Janusz, Kirby, Brian, Langford, Cordelia, Lascorz, Jesús, Leman, Joyce, Leslie, Stephen, Mallbris, Lotus, Markus, Hugh S, Mathew, Christopher G, McLean, WH Irwin, McManus, Ross, Mössner, Rotraut, Moutsianas, Loukas, Naluai, Åsa T, Nestle, Frank O, Novelli, Giuseppe, Onoufriadis, Alexandros, Palmer, Colin NA, Perricone, Carlo, Pirinen, Matti, Plomin, Robert, Potter, Simon C, Pujol, Ramon M, Rautanen, Anna, Riveira-Munoz, Eva, Ryan, Anthony W, Salmhofer, Wolfgang, Samuelsson, Lena, Sawcer, Stephen J, Schalkwijk, Joost, Smith, Catherine H, Ståhle, Mona, Su, Zhan, Tazi-Ahnini, Rachid, Traupe, Heiko, Viswanathan, Ananth C, Warren, Richard B, Weger, Wolfgang, Wolk, Katarina, Wood, Nicholas, Worthington, Jane, Young, Helen S, Zeeuwen, Patrick LJM, Hayday, Adrian, Burden, A David, Griffiths, Christopher EM, Kere, Juha, Reis, André, McVean, Gilean, Evans, David M, Brown, Matthew A, Barker, Jonathan N, Peltonen, Leena, Donnelly, Peter, Trembath, Richard C
Published 2010

Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals

by Kosmicki, Jack A., Horowitz, Julie E., Banerjee, Nilanjana, Lanche, Rouel, Marcketta, Anthony, Maxwell, Evan, Bai, Xiaodong, Sun, Dylan, Backman, Joshua D., Sharma, Deepika, Kury, Fabricio S.P., Kang, Hyun M., O’Dushlaine, Colm, Yadav, Ashish, Mansfield, Adam J., Li, Alexander H., Watanabe, Kyoko, Gurski, Lauren, McCarthy, Shane E., Locke, Adam E., Khalid, Shareef, O’Keeffe, Sean, Mbatchou, Joelle, Chazara, Olympe, Huang, Yunfeng, Kvikstad, Erika, O’Neill, Amanda, Nioi, Paul, Parker, Meg M., Petrovski, Slavé, Runz, Heiko, Szustakowski, Joseph D., Wang, Quanli, Wong, Emily, Cordova-Palomera, Aldo, Smith, Erin N., Szalma, Sandor, Zheng, Xiuwen, Esmaeeli, Sahar, Davis, Justin W., Lai, Yi-Pin, Chen, Xing, Justice, Anne E., Leader, Joseph B., Mirshahi, Tooraj, Carey, David J., Verma, Anurag, Sirugo, Giorgio, Ritchie, Marylyn D., Rader, Daniel J., Povysil, Gundula, Goldstein, David B., Kiryluk, Krzysztof, Pairo-Castineira, Erola, Rawlik, Konrad, Pasko, Dorota, Walker, Susan, Meynert, Alison, Kousathanas, Athanasios, Moutsianas, Loukas, Tenesa, Albert, Caulfield, Mark, Scott, Richard, Wilson, James F., Baillie, J. Kenneth, Butler-Laporte, Guillaume, Nakanishi, Tomoko, Lathrop, Mark, Richards, J. Brent, Jones, Marcus, Balasubramanian, Suganthi, Salerno, William, Shuldiner, Alan R., Marchini, Jonathan, Overton, John D., Habegger, Lukas, Cantor, Michael N., Reid, Jeffrey G., Baras, Aris, Abecasis, Goncalo R., Ferreira, Manuel A.R.
Published in Am J Hum Genet (2021)

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

by Evans, David M, Spencer, Chris C A, Pointon, Jennifer J, Su, Zhan, Harvey, David, Kochan, Grazyna, Oppermann, Udo, Dilthey, Alexander, Pirinen, Matti, Stone, Millicent A, Appleton, Louise, Moutsianas, Loukas, Leslie, Stephen, Wordsworth, Tom, Kenna, Tony J, Karaderi, Tugce, Thomas, Gethin P, Ward, Michael M, Weisman, Michael H, Farrar, Claire, Bradbury, Linda A, Danoy, Patrick, Inman, Robert D, Maksymowych, Walter, Gladman, Dafna, Rahman, Proton, Morgan, Ann, Marzo-Ortega, Helena, Bowness, Paul, Gaffney, Karl, Gaston, J S Hill, Smith, Malcolm, Bruges-Armas, Jacome, Couto, Ana-Rita, Sorrentino, Rosa, Paladini, Fabiana, Ferreira, Manuel A, Xu, Huji, Liu, Yu, Jiang, Lei, Lopez-Larrea, Carlos, Díaz-Peña, Roberto, López-Vázquez, Antonio, Zayats, Tetyana, Band, Gavin, Bellenguez, Céline, Blackburn, Hannah, Blackwell, Jenefer M, Bramon, Elvira, Bumpstead, Suzannah J, Casas, Juan P, Corvin, Aiden, Craddock, Nicholas, Deloukas, Panos, Dronov, Serge, Duncanson, Audrey, Edkins, Sarah, Freeman, Colin, Gillman, Matthew, Gray, Emma, Gwilliam, Rhian, Hammond, Naomi, Hunt, Sarah E, Jankowski, Janusz, Jayakumar, Alagurevathi, Langford, Cordelia, Liddle, Jennifer, Markus, Hugh S, Mathew, Christopher G, McCann, Owen T, McCarthy, Mark I, Palmer, Colin N A, Peltonen, Leena, Plomin, Robert, Potter, Simon C, Rautanen, Anna, Ravindrarajah, Radhi, Ricketts, Michelle, Samani, Nilesh, Sawcer, Stephen J, Strange, Amy, Trembath, Richard C, Viswanathan, Ananth C, Waller, Matthew, Weston, Paul, Whittaker, Pamela, Widaa, Sara, Wood, Nicholas W, McVean, Gilean, Reveille, John D, Wordsworth, B Paul, Brown, Matthew A, Donnelly, Peter
Published 2011

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

by Beecham, Ashley H, Patsopoulos, Nikolaos A, Xifara, Dionysia K, Davis, Mary F, Kemppinen, Anu, Cotsapas, Chris, Shahi, Tejas S, Spencer, Chris, Booth, David, Goris, An, Oturai, Annette, Saarela, Janna, Fontaine, Bertrand, Hemmer, Bernhard, Martin, Claes, Zipp, Frauke, D’alfonso, Sandra, Martinelli-Boneschi, Filippo, Taylor, Bruce, Harbo, Hanne F, Kockum, Ingrid, Hillert, Jan, Olsson, Tomas, Ban, Maria, Oksenberg, Jorge R, Hintzen, Rogier, Barcellos, Lisa F, Agliardi, Cristina, Alfredsson, Lars, Alizadeh, Mehdi, Anderson, Carl, Andrews, Robert, Søndergaard, Helle Bach, Baker, Amie, Band, Gavin, Baranzini, Sergio E, Barizzone, Nadia, Barrett, Jeffrey, Bellenguez, Céline, Bergamaschi, Laura, Bernardinelli, Luisa, Berthele, Achim, Biberacher, Viola, Binder, Thomas M C, Blackburn, Hannah, Bomfim, Izaura L, Brambilla, Paola, Broadley, Simon, Brochet, Bruno, Brundin, Lou, Buck, Dorothea, Butzkueven, Helmut, Caillier, Stacy J, Camu, William, Carpentier, Wassila, Cavalla, Paola, Celius, Elisabeth G, Coman, Irène, Comi, Giancarlo, Corrado, Lucia, Cosemans, Leentje, Cournu-Rebeix, Isabelle, Cree, Bruce A C, Cusi, Daniele, Damotte, Vincent, Defer, Gilles, Delgado, Silvia R, Deloukas, Panos, di Sapio, Alessia, Dilthey, Alexander T, Donnelly, Peter, Dubois, Bénédicte, Duddy, Martin, Edkins, Sarah, Elovaara, Irina, Esposito, Federica, Evangelou, Nikos, Fiddes, Barnaby, Field, Judith, Franke, Andre, Freeman, Colin, Frohlich, Irene Y, Galimberti, Daniela, Gieger, Christian, Gourraud, Pierre-Antoine, Graetz, Christiane, Graham, Andrew, Grummel, Verena, Guaschino, Clara, Hadjixenofontos, Athena, Hakonarson, Hakon, Halfpenny, Christopher, Hall, Gillian, Hall, Per, Hamsten, Anders, Harley, James, Harrower, Timothy, Hawkins, Clive, Hellenthal, Garrett, Hillier, Charles, Hobart, Jeremy, Hoshi, Muni, Hunt, Sarah E, Jagodic, Maja, Jelčić, Ilijas, Jochim, Angela, Kendall, Brian, Kermode, Allan, Kilpatrick, Trevor, Koivisto, Keijo, Konidari, Ioanna, Korn, Thomas, Kronsbein, Helena, Langford, Cordelia, Larsson, Malin, Lathrop, Mark, Lebrun-Frenay, Christine, Lechner-Scott, Jeannette, Lee, Michelle H, Leone, Maurizio A, Leppä, Virpi, Liberatore, Giuseppe, Lie, Benedicte A, Lill, Christina M, Lindén, Magdalena, Link, Jenny, Luessi, Felix, Lycke, Jan, Macciardi, Fabio, Männistö, Satu, Manrique, Clara P, Martin, Roland, Martinelli, Vittorio, Mason, Deborah, Mazibrada, Gordon, McCabe, Cristin, Mero, Inger-Lise, Mescheriakova, Julia, Moutsianas, Loukas, Myhr, Kjell-Morten, Nagels, Guy, Nicholas, Richard, Nilsson, Petra, Piehl, Fredrik, Pirinen, Matti, Price, Siân E, Quach, Hong, Reunanen, Mauri, Robberecht, Wim, Robertson, Neil P, Rodegher, Mariaemma, Rog, David, Salvetti, Marco, Schnetz-Boutaud, Nathalie C, Sellebjerg, Finn, Selter, Rebecca C, Schaefer, Catherine, Shaunak, Sandip, Shen, Ling, Shields, Simon, Siffrin, Volker, Slee, Mark, Sorensen, Per Soelberg, Sorosina, Melissa, Sospedra, Mireia, Spurkland, Anne, Strange, Amy, Sundqvist, Emilie, Thijs, Vincent, Thorpe, John, Ticca, Anna, Tienari, Pentti, van Duijn, Cornelia, Visser, Elizabeth M, Vucic, Steve, Westerlind, Helga, Wiley, James S, Wilkins, Alastair, Wilson, James F, Winkelmann, Juliane, Zajicek, John, Zindler, Eva, Haines, Jonathan L, Pericak-Vance, Margaret A, Ivinson, Adrian J, Stewart, Graeme, Hafler, David, Hauser, Stephen L, Compston, Alastair, McVean, Gil, De Jager, Philip, Sawcer, Stephen, McCauley, Jacob L
Published 2013

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

by Sawcer, Stephen, Hellenthal, Garrett, Pirinen, Matti, Spencer, Chris C.A., Patsopoulos, Nikolaos A., Moutsianas, Loukas, Dilthey, Alexander, Su, Zhan, Freeman, Colin, Hunt, Sarah E., Edkins, Sarah, Gray, Emma, Booth, David R., Potter, Simon C., Goris, An, Band, Gavin, Oturai, Annette Bang, Strange, Amy, Saarela, Janna, Bellenguez, Céline, Fontaine, Bertrand, Gillman, Matthew, Hemmer, Bernhard, Gwilliam, Rhian, Zipp, Frauke, Jayakumar, Alagurevathi, Martin, Roland, Leslie, Stephen, Hawkins, Stanley, Giannoulatou, Eleni, D’alfonso, Sandra, Blackburn, Hannah, Boneschi, Filippo Martinelli, Liddle, Jennifer, Harbo, Hanne F., Perez, Marc L., Spurkland, Anne, Waller, Matthew J, Mycko, Marcin P., Ricketts, Michelle, Comabella, Manuel, Hammond, Naomi, Kockum, Ingrid, McCann, Owen T., Ban, Maria, Whittaker, Pamela, Kemppinen, Anu, Weston, Paul, Hawkins, Clive, Widaa, Sara, Zajicek, John, Dronov, Serge, Robertson, Neil, Bumpstead, Suzannah J., Barcellos, Lisa F., Ravindrarajah, Rathi, Abraham, Roby, Alfredsson, Lars, Ardlie, Kristin, Aubin, Cristin, Baker, Amie, Baker, Katharine, Baranzini, Sergio E., Bergamaschi, Laura, Bergamaschi, Roberto, Bernstein, Allan, Berthele, Achim, Boggild, Mike, Bradfield, Jonathan P., Brassat, David, Broadley, Simon A., Buck, Dorothea, Butzkueven, Helmut, Capra, Ruggero, Carroll, William M., Cavalla, Paola, Celius, Elisabeth G., Cepok, Sabine, Chiavacci, Rosetta, Clerget-Darpoux, Françoise, Clysters, Katleen, Comi, Giancarlo, Cossburn, Mark, Cournu-Rebeix, Isabelle, Cox, Mathew B., Cozen, Wendy, Cree, Bruce A.C., Cross, Anne H., Cusi, Daniele, Daly, Mark J., Davis, Emma, de Bakker, Paul I.W., Debouverie, Marc, D’hooghe, Marie Beatrice, Dixon, Katherine, Dobosi, Rita, Dubois, Bénédicte, Ellinghaus, David, Elovaara, Irina, Esposito, Federica, Fontenille, Claire, Foote, Simon, Franke, Andre, Galimberti, Daniela, Ghezzi, Angelo, Glessner, Joseph, Gomez, Refujia, Gout, Olivier, Graham, Colin, Grant, Struan F.A., Guerini, Franca Rosa, Hakonarson, Hakon, Hall, Per, Hamsten, Anders, Hartung, Hans-Peter, Heard, Rob N., Heath, Simon, Hobart, Jeremy, Hoshi, Muna, Infante-Duarte, Carmen, Ingram, Gillian, Ingram, Wendy, Islam, Talat, Jagodic, Maja, Kabesch, Michael, Kermode, Allan G., Kilpatrick, Trevor J., Kim, Cecilia, Klopp, Norman, Koivisto, Keijo, Larsson, Malin, Lathrop, Mark, Lechner-Scott, Jeannette S., Leone, Maurizio A., Leppä, Virpi, Liljedahl, Ulrika, Bomfim, Izaura Lima, Lincoln, Robin R., Link, Jenny, Liu, Jianjun, Lorentzen, Åslaug R., Lupoli, Sara, Macciardi, Fabio, Mack, Thomas, Marriott, Mark, Martinelli, Vittorio, Mason, Deborah, McCauley, Jacob L., Mentch, Frank, Mero, Inger-Lise, Mihalova, Tania, Montalban, Xavier, Mottershead, John, Myhr, Kjell-Morten, Naldi, Paola, Ollier, William, Page, Alison, Palotie, Aarno, Pelletier, Jean, Piccio, Laura, Pickersgill, Trevor, Piehl, Fredrik, Pobywajlo, Susan, Quach, Hong L., Ramsay, Patricia P., Reunanen, Mauri, Reynolds, Richard, Rioux, John D., Rodegher, Mariaemma, Roesner, Sabine, Rubio, Justin P., Rückert, Ina-Maria, Salvetti, Marco, Salvi, Erika, Santaniello, Adam, Schaefer, Catherine A., Schreiber, Stefan, Schulze, Christian, Scott, Rodney J., Sellebjerg, Finn, Selmaj, Krzysztof W., Sexton, David, Shen, Ling, Simms-Acuna, Brigid, Skidmore, Sheila, Sleiman, Patrick M.A., Smestad, Cathrine, Sørensen, Per Soelberg, Søndergaard, Helle Bach, Stankovich, Jim, Strange, Richard C., Sulonen, Anna-Maija, Sundqvist, Emilie, Syvänen, Ann-Christine, Taddeo, Francesca, Taylor, Bruce, Blackwell, Jenefer M., Tienari, Pentti, Bramon, Elvira, Tourbah, Ayman, Brown, Matthew A., Tronczynska, Ewa, Casas, Juan P., Tubridy, Niall, Corvin, Aiden, Vickery, Jane, Jankowski, Janusz, Villoslada, Pablo, Markus, Hugh S., Wang, Kai, Mathew, Christopher G., Wason, James, Palmer, Colin N.A., Wichmann, H-Erich, Plomin, Robert, Willoughby, Ernest, Rautanen, Anna, Winkelmann, Juliane, Wittig, Michael, Trembath, Richard C., Yaouanq, Jacqueline, Viswanathan, Ananth C., Zhang, Haitao, Wood, Nicholas W., Zuvich, Rebecca, Deloukas, Panos, Langford, Cordelia, Duncanson, Audrey, Oksenberg, Jorge R., Pericak-Vance, Margaret A., Haines, Jonathan L., Olsson, Tomas, Hillert, Jan, Ivinson, Adrian J., De Jager, Philip L., Peltonen, Leena, Stewart, Graeme J., Hafler, David A., Hauser, Stephen L., McVean, Gil, Donnelly, Peter, Compston, Alastair
Published 2011

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

by Manning, Alisa, Highland, Heather M., Gasser, Jessica, Sim, Xueling, Tukiainen, Taru, Fontanillas, Pierre, Grarup, Niels, Rivas, Manuel A., Mahajan, Anubha, Locke, Adam E., Cingolani, Pablo, Pers, Tune H., Viñuela, Ana, Brown, Andrew A., Wu, Ying, Flannick, Jason, Fuchsberger, Christian, Gamazon, Eric R., Gaulton, Kyle J., Im, Hae Kyung, Teslovich, Tanya M., Blackwell, Thomas W., Bork-Jensen, Jette, Burtt, Noël P., Chen, Yuhui, Green, Todd, Hartl, Christopher, Kang, Hyun Min, Kumar, Ashish, Ladenvall, Claes, Ma, Clement, Moutsianas, Loukas, Pearson, Richard D., Perry, John R.B., Rayner, N. William, Robertson, Neil R., Scott, Laura J., van de Bunt, Martijn, Eriksson, Johan G., Jula, Antti, Koskinen, Seppo, Lehtimäki, Terho, Palotie, Aarno, Raitakari, Olli T., Jacobs, Suzanne B.R., Wessel, Jennifer, Chu, Audrey Y., Scott, Robert A., Goodarzi, Mark O., Blancher, Christine, Buck, Gemma, Buck, David, Chines, Peter S., Gabriel, Stacey, Gjesing, Anette P., Groves, Christopher J., Hollensted, Mette, Huyghe, Jeroen R., Jackson, Anne U., Jun, Goo, Justesen, Johanne Marie, Mangino, Massimo, Murphy, Jacquelyn, Neville, Matt, Onofrio, Robert, Small, Kerrin S., Stringham, Heather M., Trakalo, Joseph, Banks, Eric, Carey, Jason, Carneiro, Mauricio O., DePristo, Mark, Farjoun, Yossi, Fennell, Timothy, Goldstein, Jacqueline I., Grant, George, Hrabé de Angelis, Martin, Maguire, Jared, Neale, Benjamin M., Poplin, Ryan, Purcell, Shaun, Schwarzmayr, Thomas, Shakir, Khalid, Smith, Joshua D., Strom, Tim M., Wieland, Thomas, Lindstrom, Jaana, Brandslund, Ivan, Christensen, Cramer, Surdulescu, Gabriela L., Lakka, Timo A., Doney, Alex S.F., Nilsson, Peter, Wareham, Nicholas J., Langenberg, Claudia, Varga, Tibor V., Franks, Paul W., Rolandsson, Olov, Rosengren, Anders H., Farook, Vidya S., Thameem, Farook, Puppala, Sobha, Kumar, Satish, Lehman, Donna M., Jenkinson, Christopher P., Curran, Joanne E., Hale, Daniel Esten, Fowler, Sharon P., Arya, Rector, DeFronzo, Ralph A., Abboud, Hanna E., Syvänen, Ann-Christine, Hicks, Pamela J., Palmer, Nicholette D., Ng, Maggie C.Y., Bowden, Donald W., Freedman, Barry I., Esko, Tõnu, Mägi, Reedik, Milani, Lili, Mihailov, Evelin, Metspalu, Andres, Narisu, Narisu, Kinnunen, Leena, Bonnycastle, Lori L., Swift, Amy, Pasko, Dorota, Wood, Andrew R., Fadista, João, Pollin, Toni I., Barzilai, Nir, Atzmon, Gil, Glaser, Benjamin, Thorand, Barbara, Strauch, Konstantin, Peters, Annette, Roden, Michael, Müller-Nurasyid, Martina, Liang, Liming, Kriebel, Jennifer, Illig, Thomas, Grallert, Harald, Gieger, Christian, Meisinger, Christa, Lannfelt, Lars, Musani, Solomon K., Griswold, Michael, Taylor, Herman A., Wilson, Gregory, Correa, Adolfo, Oksa, Heikki, Scott, William R., Afzal, Uzma, Tan, Sian-Tsung, Loh, Marie, Chambers, John C., Sehmi, Jobanpreet, Kooner, Jaspal Singh, Lehne, Benjamin, Cho, Yoon Shin, Lee, Jong-Young, Han, Bok-Ghee, Käräjämäki, Annemari, Qi, Qibin, Qi, Lu, Huang, Jinyan, Hu, Frank B., Melander, Olle, Orho-Melander, Marju, Below, Jennifer E., Aguilar, David, Wong, Tien Yin, Liu, Jianjun, Khor, Chiea-Chuen, Chia, Kee Seng, Lim, Wei Yen, Cheng, Ching-Yu, Chan, Edmund, Tai, E Shyong, Aung, Tin, Linneberg, Allan, Isomaa, Bo, Meitinger, Thomas, Tuomi, Tiinamaija, Hakaste, Liisa, Kravic, Jasmina, Jørgensen, Marit E., Lauritzen, Torsten, Deloukas, Panos, Stirrups, Kathleen E., Owen, Katharine R., Farmer, Andrew J., Frayling, Timothy M., O'Rahilly, Stephen P., Walker, Mark, Levy, Jonathan C., Hodgkiss, Dylan, Hattersley, Andrew T., Kuulasmaa, Teemu, Stančáková, Alena, Barroso, Inês, Bharadwaj, Dwaipayan, Chan, Juliana, Chandak, Giriraj R., Daly, Mark J., Donnelly, Peter J., Ebrahim, Shah B., Elliott, Paul, Fingerlin, Tasha, Froguel, Philippe, Hu, Cheng, Jia, Weiping, Ma, Ronald C.W., McVean, Gilean, Park, Taesung, Prabhakaran, Dorairaj, Sandhu, Manjinder, Scott, James, Sladek, Rob, Tandon, Nikhil, Teo, Yik Ying, Zeggini, Eleftheria, Watanabe, Richard M., Koistinen, Heikki A., Kesaniemi, Y. Antero, Uusitupa, Matti, Spector, Timothy D., Salomaa, Veikko, Rauramaa, Rainer, Palmer, Colin N.A., Prokopenko, Inga, Morris, Andrew D., Bergman, Richard N., Collins, Francis S., Lind, Lars, Ingelsson, Erik, Tuomilehto, Jaakko, Karpe, Fredrik, Groop, Leif, Jørgensen, Torben, Hansen, Torben, Pedersen, Oluf, Kuusisto, Johanna, Abecasis, Gonçalo, Bell, Graeme I., Blangero, John, Cox, Nancy J., Duggirala, Ravindranath, Seielstad, Mark, Wilson, James G., Dupuis, Josee, Ripatti, Samuli, Hanis, Craig L., Florez, Jose C., Mohlke, Karen L., Meigs, James B., Laakso, Markku, Morris, Andrew P., Boehnke, Michael, Altshuler, David, McCarthy, Mark I., Gloyn, Anna L., Lindgren, Cecilia M.
Published in Diabetes (2017)