Drug advances in inflammatory bowel disease

Por Speight, R Alexander, Mansfield, John C
Publicado no Clin Med (Lond) (2013)

Sexually transmitted infections manifesting as proctitis

Por Lamb, Chris A, Lamb, Elizabeth Iris Mary, Mansfield, John C, Sankar, K Nathan
Publicado em 2013

Measurement methods and accuracy in copy number variation: failure to replicate associations of beta-defensin copy number with Crohn's disease

Por Aldhous, Marian C., Abu Bakar, Suhaili, Prescott, Natalie J., Palla, Raquel, Soo, Kimberley, Mansfield, John C., Mathew, Christopher G., Satsangi, Jack, Armour, John A.L.
Publicado em 2010

Searching for Genotype-Phenotype Structure: Using Hierarchical Log-Linear Models in Crohn Disease

Por Chapman, Juliet M., Onnie, Clive M., Prescott, Natalie J., Fisher, Sheila A., Mansfield, John C., Mathew, Christopher G., Lewis, Cathryn M., Verzilli, Claudio J., Whittaker, John C.
Publicado em 2009

A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis

Por Rutgeerts, Paul J, Fedorak, Richard N, Hommes, Daan W, Sturm, Andreas, Baumgart, Daniel C, Bressler, Brian, Schreiber, Stefan, Mansfield, John C, Williams, Marna, Tang, Meina, Visich, Jennifer, Wei, Xiaohui, Keir, Mary, Luca, Diana, Danilenko, Dimitri, Egen, Jackson, O'Byrne, Sharon
Publicado em 2013

Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease

Por Prescott, Natalie J., Dominy, Katherine M., Kubo, Michiaki, Lewis, Cathryn M., Fisher, Sheila A., Redon, Richard, Huang, Ni, Stranger, Barbara E., Blaszczyk, Katarzyna, Hudspith, Barry, Parkes, Gareth, Hosono, Naoya, Yamazaki, Keiko, Onnie, Clive M., Forbes, Alastair, Dermitzakis, Emmanouil T., Nakamura, Yusuke, Mansfield, John C., Sanderson, Jeremy, Hurles, Matthew E., Roberts, Roland G., Mathew, Christopher G.
Publicado em 2010

Human SNP Links Differential Outcomes in Inflammatory and Infectious Disease to a FOXO3-Regulated Pathway

Por Lee, James C., Espéli, Marion, Anderson, Carl A., Linterman, Michelle A., Pocock, Joanna M., Williams, Naomi J., Roberts, Rebecca, Viatte, Sebastien, Fu, Bo, Peshu, Norbert, Hien, Tran Tinh, Phu, Nguyen Hoan, Wesley, Emma, Edwards, Cathryn, Ahmad, Tariq, Mansfield, John C., Gearry, Richard, Dunstan, Sarah, Williams, Thomas N., Barton, Anne, Vinuesa, Carola G., Parkes, Miles, Lyons, Paul A., Smith, Kenneth G.C.
Publicado em 2013

Pooled Sequencing of 531 Genes in Inflammatory Bowel Disease Identifies an Associated Rare Variant in BTNL2 and Implicates Other Immune Related Genes

Por Prescott, Natalie J., Lehne, Benjamin, Stone, Kristina, Lee, James C., Taylor, Kirstin, Knight, Jo, Papouli, Efterpi, Mirza, Muddassar M., Simpson, Michael A., Spain, Sarah L., Lu, Grace, Fraternali, Franca, Bumpstead, Suzannah J., Gray, Emma, Amar, Ariella, Bye, Hannah, Green, Peter, Chung-Faye, Guy, Hayee, Bu’Hussain, Pollok, Richard, Satsangi, Jack, Parkes, Miles, Barrett, Jeffrey C., Mansfield, John C., Sanderson, Jeremy, Lewis, Cathryn M., Weale, Michael E., Schlitt, Thomas, Mathew, Christopher G.
Publicado no PLoS Genet (2015)

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn disease susceptibility

Por Parkes, Miles, Barrett, Jeffrey C, Prescott, Natalie, Tremelling, Mark, Anderson, Carl A, Fisher, Sheila A, Roberts, Roland G, Nimmo, Elaine R, Cummings, Fraser R, Soars, Dianne, Drummond, Hazel, Lees, Charlie W, Khawaja, Saud A, Bagnall, Richard, Burke, Denis A, Todhunter, Catherine E, Ahmad, Tariq, Onnie, Clive M, McArdle, Wendy, Strachan, David, Bethel, Graeme, Bryan, Claire, Deloukas, Panos, Forbes, Alastair, Sanderson, Jeremy, Jewell, Derek P, Satsangi, Jack, Mansfield, John C, Cardon, Lon, Mathew, Christopher G
Publicado em 2007

Exploring the genetic architecture of inflammatory bowel disease by whole genome sequencing identifies association at ADCY7

Por Luo, Yang, de Lange, Katrina M., Jostins, Luke, Moutsianas, Loukas, Randall, Joshua, Kennedy, Nicholas A., Lamb, Christopher A., McCarthy, Shane, Ahmad, Tariq, Edwards, Cathryn, Serra, Eva Goncalves, Hart, Ailsa, Hawkey, Chris, Mansfield, John C., Mowat, Craig, Newman, William G., Nichols, Sam, Pollard, Martin, Satsangi, Jack, Simmons, Alison, Tremelling, Mark, Uhlig, Holm, Wilson, David C., Lee, James C., Prescott, Natalie J., Lees, Charlie W., Mathew, Christopher G., Parkes, Miles, Barrett, Jeffrey C., Anderson, Carl A.
Publicado no Nat Genet (2017)

Investigation of Crohn’s Disease Risk Loci in Ulcerative Colitis Further Defines Their Molecular Relationship

Por ANDERSON, CARL A., MASSEY, DUNECAN C. O., BARRETT, JEFFREY C., PRESCOTT, NATALIE J., TREMELLING, MARK, FISHER, SHEILA A., GWILLIAM, RHIAN, JACOB, JEMIMA, NIMMO, ELAINE R., DRUMMOND, HAZEL, LEES, CHARLIE W., ONNIE, CLIVE M., HANSON, CATHERINE, BLASZCZYK, KATARZYNA, RAVINDRARAJAH, RADHI, HUNT, SARAH, VARMA, DHIRAJ, HAMMOND, NAOMI, LEWIS, GREGORY, ATTLESEY, HEATHER, WATKINS, NICK, OUWEHAND, WILLEM, STRACHAN, DAVID, MCARDLE, WENDY, LEWIS, CATHRYN M., LOBO, ALAN, SANDERSON, JEREMY, JEWELL, DEREK P., DELOUKAS, PANOS, MANSFIELD, JOHN C., MATHEW, CHRISTOPHER G., SATSANGI, JACK, PARKES, MILES
Publicado em 2008

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

Por de Lange, Katrina M., Moutsianas, Loukas, Lee, James C., Lamb, Christopher A., Luo, Yang, Kennedy, Nicholas A., Jostins, Luke, Rice, Daniel L., Gutierrez-Achury, Javier, Ji, Sun-Gou, Heap, Graham, Nimmo, Elaine R., Edwards, Cathryn, Henderson, Paul, Mowat, Craig, Sanderson, Jeremy, Satsangi, Jack, Simmons, Alison, Wilson, David C., Tremelling, Mark, Hart, Ailsa, Mathew, Christopher G., Newman, William G., Parkes, Miles, Lees, Charlie W., Uhlig, Holm, Hawkey, Chris, Prescott, Natalie J., Ahmad, Tariq, Mansfield, John C., Anderson, Carl A., Barrett, Jeffrey C.
Publicado no Nat Genet (2017)

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn’s disease

Por Fisher, Sheila A, Tremelling, Mark, Anderson, Carl A, Gwilliam, Rhian, Bumpstead, Suzannah, Prescott, Natalie J, Nimmo, Elaine R, Massey, Dunecan, Berzuini, Carlo, Johnson, Christopher, Barrett, Jeffrey C, Cummings, Fraser R, Drummond, Hazel, Lees, Charlie W, Onnie, Clive M, Hanson, Catherine E, Blaszczyk, Katarzyna, Inouye, Mike, Ewels, Philip, Ravindrarajah, Radhi, Keniry, Andrew, Hunt, Sarah, Carter, Martyn, Watkins, Nick, Ouwehand, Willem, Lewis, Cathryn M, Cardon, Lon, Lobo, Alan, Forbes, Alastair, Sanderson, Jeremy, Jewell, Derek P, Mansfield, John C, Deloukas, Panos, Mathew, Christopher G, Parkes, Miles, Satsangi, Jack
Publicado em 2008

Negligible impact of rare autoimmune-locus coding-region variants on missing heritability

Por Hunt, Karen A, Mistry, Vanisha, Bockett, Nicholas A, Ahmad, Tariq, Ban, Maria, Barker, Jonathan N, Barrett, Jeffrey C, Blackburn, Hannah, Brand, Oliver, Burren, Oliver, Capon, Francesca, Compston, Alastair, Gough, Stephen CL, Jostins, Luke, Kong, Yong, Lee, James C, Lek, Monkol, MacArthur, Daniel G, Mansfield, John C, Mathew, Christopher G, Mein, Charles A, Mirza, Muddassar, Nutland, Sarah, Onengut-Gumuscu, Suna, Papouli, Efterpi, Parkes, Miles, Rich, Stephen S., Sawcer, Steven, Satsangi, Jack, Simmonds, Matthew J, Trembath, Richard C, Walker, Neil M, Wozniak, Eva, Todd, John A, Simpson, Michael A, Plagnol, Vincent, van Heel, David A
Publicado em 2013

Meta-Analysis Increases to 71 the Tally of Confirmed Crohn’s Disease Susceptibility Loci

Por Franke, Andre, McGovern, Dermot P.B., Barrett, Jeffrey C., Wang, Kai, Radford-Smith, Graham L., Ahmad, Tariq, Lees, Charlie W., Balschun, Tobias, Lee, James, Roberts, Rebecca, Anderson, Carl A., Bis, Joshua C., Bumpstead, Suzanne, Ellinghaus, David, Festen, Eleonora M., Georges, Michel, Haritunians, Talin, Jostins, Luke, Latiano, Anna, Mathew, Christopher G., Montgomery, Grant W., Prescott, Natalie J., Rotter, Jerome I., Schumm, Philip, Sharma, Yashoda, Simms, Lisa A., Taylor, Kent D., Whiteman, David, Wijmenga, Cisca, Baldassano, Robert N., Barclay, Murray, Bayless, Theodore M., Brand, Stephan, Buning, Carsten, Cohen, Albert, Colombel, Jean-Frederick, Cottone, Mario, Stronati, Laura, Denson, Ted, De Vos, Martine, D’Inca, Renata, Dubinsky, Marla, Edwards, Cathryn, Florin, Tim, Franchimont, Denis, Gearry, Richard, Glas, Jürgen, Van Gossum, Andre, Guthery, Stephen L., Halfvarson, Jonas, Hommes, Daan, Hugot, Jean-Pierre, Laukens, Debby, Lawrance, Ian, Lemann, Marc, Levine, Arie, Libioulle, Cecile, Louis, Edouard, Mowat, Craig, Newman, William, Panés, Julián, Phillips, Anne, Proctor, Deborah D., Regueiro, Miguel, Rutgeerts, Paul, Sanderson, Jeremy, Sans, Miquel, Seibold, Frank, Steinhart, A. Hillary, Stokkers, Pieter C.F., Torkvist, Leif, Ublick, Gerd Kullak, Raychaudhuri, Soumya, Green, Todd, Walters, Thomas, Targan, Stephan R., Brant, Steven R., Rioux, John D., D’Amato, Mauro, Weersma, Rinse, Kugathasan, Subra, Griffiths, Anne M., Mansfield, John C., Vermeire, Severine, Duerr, Richard H., Silverberg, Mark S., Satsangi, Jack, Schreiber, Stefan, Cho, Judy H., Annese, Vito, Hakonarson, Hakon, Daly, Mark J., Parkes, Miles
Publicado em 2010

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

Por Anderson, Carl A., Boucher, Gabrielle, Lees, Charlie W., Franke, Andre, D’Amato, Mauro, Taylor, Kent D., Lee, James C., Goyette, Philippe, Imielinski, Marcin, Latiano, Anna, Lagacé, Caroline, Scott, Regan, Amininejad, Leila, Bumpstead, Suzannah, Baidoo, Leonard, Baldassano, Robert N., Barclay, Murray, Bayless, Theodore M., Brand, Stephan, Büning, Carsten, Colombel, Jean-Frédéric, Denson, Lee A., De Vos, Martine, Dubinsky, Marla, Edwards, Cathryn, Ellinghaus, David, Fehrmann, Rudolf S.N., Floyd, James A.B., Florin, Tim, Franchimont, Denis, Franke, Lude, Georges, Michel, Glas, Jürgen, Glazer, Nicole L., Guthery, Stephen L., Haritunians, Talin, Hayward, Nicholas K., Hugot, Jean-Pierre, Jobin, Gilles, Laukens, Debby, Lawrance, Ian, Lémann, Marc, Levine, Arie, Libioulle, Cecile, Louis, Edouard, McGovern, Dermot P., Milla, Monica, Montgomery, Grant W., Morley, Katherine I., Mowat, Craig, Ng, Aylwin, Newman, William, Ophoff, Roel A, Papi, Laura, Palmieri, Orazio, Peyrin-Biroulet, Laurent, Panés, Julián, Phillips, Anne, Prescott, Natalie J., Proctor, Deborah D., Roberts, Rebecca, Russell, Richard, Rutgeerts, Paul, Sanderson, Jeremy, Sans, Miquel, Schumm, Philip, Seibold, Frank, Sharma, Yashoda, Simms, Lisa, Seielstad, Mark, Steinhart, A. Hillary, Targan, Stephan R., van den Berg, Leonard H., Vatn, Morten, Verspaget, Hein, Walters, Thomas, Wijmenga, Cisca, Wilson, David C., Westra, Harm-Jan, Xavier, Ramnik J., Zhao, Zhen Z., Ponsioen, Cyriel Y., Andersen, Vibeke, Torkvist, Leif, Gazouli, Maria, Anagnou, Nicholas P., Karlsen, Tom H., Kupcinskas, Limas, Sventoraityte, Jurgita, Mansfield, John C., Kugathasan, Subra, Silverberg, Mark S., Halfvarson, Jonas, Rotter, Jerome I., Mathew, Christopher G., Griffiths, Anne M., Gearry, Richard, Ahmad, Tariq, Brant, Steven R., Chamaillard, Mathias, Satsangi, Jack, Cho, Judy H., Schreiber, Stefan, Daly, Mark J., Barrett, Jeffrey C., Parkes, Miles, Annese, Vito, Hakonarson, Hakon, Radford-Smith, Graham, Duerr, Richard H., Vermeire, Séverine, Weersma, Rinse K., Rioux, John D.
Publicado em 2011