Regulators of homologous recombination repair as novel targets for cancer treatment

Por Krajewska, Małgorzata, Fehrmann, Rudolf S. N., de Vries, Elisabeth G. E., van Vugt, Marcel A. T. M.
Publicado no Front Genet (2015)

Growth Differentiation Factor 15 (GDF-15) Plasma Levels Increase during Bleomycin- and Cisplatin-Based Treatment of Testicular Cancer Patients and Relate to Endothelial Damage

Por Altena, Renske, Fehrmann, Rudolf S. N., Boer, Hink, de Vries, Elisabeth G. E., Meijer, Coby, Gietema, Jourik A.
Publicado no PLoS One (2015)

Functional Genomic mRNA Profiling of a large cancer data base demonstrates mesothelin overexpression in a broad range of tumor types

Por Lamberts, Laetitia E., de Groot, Derk Jan A., Bense, Rico D., de Vries, Elisabeth G.E., Fehrmann, Rudolf S.N.
Publicado no Oncotarget (2015)

Functional Genomic mRNA Profiling of Colorectal Adenomas: Identification and in vivo Validation of CD44 and Splice Variant CD44v6 as Molecular Imaging Targets

Por Hartmans, Elmire, Orian-Rousseau, Veronique, Matzke-Ogi, Alexandra, Karrenbeld, Arend, de Groot, Derk Jan A., de Jong, Steven, van Dam, Gooitzen M., Fehrmann, Rudolf S.N., Nagengast, Wouter B.
Publicado no Theranostics (2017)

Human Disease-Associated Genetic Variation Impacts Large Intergenic Non-Coding RNA Expression

Por Kumar, Vinod, Westra, Harm-Jan, Karjalainen, Juha, Zhernakova, Daria V., Esko, Tõnu, Hrdlickova, Barbara, Almeida, Rodrigo, Zhernakova, Alexandra, Reinmaa, Eva, Võsa, Urmo, Hofker, Marten H., Fehrmann, Rudolf S. N., Fu, Jingyuan, Withoff, Sebo, Metspalu, Andres, Franke, Lude, Wijmenga, Cisca
Publicado em 2013

Survival-Related Profile, Pathways, and Transcription Factors in Ovarian Cancer

Por Crijns, Anne P. G, Fehrmann, Rudolf S. N, de Jong, Steven, Gerbens, Frans, Meersma, Gert Jan, Klip, Harry G, Hollema, Harry, Hofstra, Robert M. W, te Meerman, Gerard J., de Vries, Elisabeth G. E, van der Zee, Ate G. J
Publicado em 2009

Evidence Based Selection of Housekeeping Genes

Por de Jonge, Hendrik J. M., Fehrmann, Rudolf S. N., de Bont, Eveline S. J. M., Hofstra, Robert M. W., Gerbens, Frans, Kamps, Willem A., de Vries, Elisabeth G. E., van der Zee, Ate G. J., te Meerman, Gerard J., ter Elst, Arja
Publicado em 2007

Biological interpretation of genome-wide association studies using predicted gene functions

Por Pers, Tune H., Karjalainen, Juha M., Chan, Yingleong, Westra, Harm-Jan, Wood, Andrew R., Yang, Jian, Lui, Julian C., Vedantam, Sailaja, Gustafsson, Stefan, Esko, Tonu, Frayling, Tim, Speliotes, Elizabeth K., Boehnke, Michael, Raychaudhuri, Soumya, Fehrmann, Rudolf S.N., Hirschhorn, Joel N., Franke, Lude
Publicado no Nat Commun (2015)

A New Perspective on Transcriptional System Regulation (TSR): Towards TSR Profiling

Por Fehrmann, Rudolf S. N., de Jonge, Hendrik J. M., ter Elst, Arja, de Vries, André, Crijns, Anne G. P., Weidenaar, Alida C., Gerbens, Frans, de Jong, Steven, van der Zee, Ate G. J., de Vries, Elisabeth G. E., Kamps, Willem A., Hofstra, Robert M. W., te Meerman, Gerard J., de Bont, Eveline S. J. M.
Publicado em 2008

Unraveling the Regulatory Mechanisms Underlying Tissue-Dependent Genetic Variation of Gene Expression

Por Fu, Jingyuan, Wolfs, Marcel G. M., Deelen, Patrick, Westra, Harm-Jan, Fehrmann, Rudolf S. N., te Meerman, Gerard J., Buurman, Wim A., Rensen, Sander S. M., Groen, Harry J. M., Weersma, Rinse K., van den Berg, Leonard H., Veldink, Jan, Ophoff, Roel A., Snieder, Harold, van Heel, David, Jansen, Ritsert C., Hofker, Marten H., Wijmenga, Cisca, Franke, Lude
Publicado em 2012

Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA

Por Fehrmann, Rudolf S. N., Jansen, Ritsert C., Veldink, Jan H., Westra, Harm-Jan, Arends, Danny, Bonder, Marc Jan, Fu, Jingyuan, Deelen, Patrick, Groen, Harry J. M., Smolonska, Asia, Weersma, Rinse K., Hofstra, Robert M. W., Buurman, Wim A., Rensen, Sander, Wolfs, Marcel G. M., Platteel, Mathieu, Zhernakova, Alexandra, Elbers, Clara C., Festen, Eleanora M., Trynka, Gosia, Hofker, Marten H., Saris, Christiaan G. J., Ophoff, Roel A., van den Berg, Leonard H., van Heel, David A., Wijmenga, Cisca, te Meerman, Gerard J., Franke, Lude
Publicado em 2011

Meta-Analysis of Genome-Wide Association Studies in Celiac Disease and Rheumatoid Arthritis Identifies Fourteen Non-HLA Shared Loci

Por Zhernakova, Alexandra, Stahl, Eli A., Trynka, Gosia, Raychaudhuri, Soumya, Festen, Eleanora A., Franke, Lude, Westra, Harm-Jan, Fehrmann, Rudolf S. N., Kurreeman, Fina A. S., Thomson, Brian, Gupta, Namrata, Romanos, Jihane, McManus, Ross, Ryan, Anthony W., Turner, Graham, Brouwer, Elisabeth, Posthumus, Marcel D., Remmers, Elaine F., Tucci, Francesca, Toes, Rene, Grandone, Elvira, Mazzilli, Maria Cristina, Rybak, Anna, Cukrowska, Bozena, Coenen, Marieke J. H., Radstake, Timothy R. D. J., van Riel, Piet L. C. M., Li, Yonghong, de Bakker, Paul I. W., Gregersen, Peter K., Worthington, Jane, Siminovitch, Katherine A., Klareskog, Lars, Huizinga, Tom W. J., Wijmenga, Cisca, Plenge, Robert M.
Publicado em 2011

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

Por Anderson, Carl A., Boucher, Gabrielle, Lees, Charlie W., Franke, Andre, D’Amato, Mauro, Taylor, Kent D., Lee, James C., Goyette, Philippe, Imielinski, Marcin, Latiano, Anna, Lagacé, Caroline, Scott, Regan, Amininejad, Leila, Bumpstead, Suzannah, Baidoo, Leonard, Baldassano, Robert N., Barclay, Murray, Bayless, Theodore M., Brand, Stephan, Büning, Carsten, Colombel, Jean-Frédéric, Denson, Lee A., De Vos, Martine, Dubinsky, Marla, Edwards, Cathryn, Ellinghaus, David, Fehrmann, Rudolf S.N., Floyd, James A.B., Florin, Tim, Franchimont, Denis, Franke, Lude, Georges, Michel, Glas, Jürgen, Glazer, Nicole L., Guthery, Stephen L., Haritunians, Talin, Hayward, Nicholas K., Hugot, Jean-Pierre, Jobin, Gilles, Laukens, Debby, Lawrance, Ian, Lémann, Marc, Levine, Arie, Libioulle, Cecile, Louis, Edouard, McGovern, Dermot P., Milla, Monica, Montgomery, Grant W., Morley, Katherine I., Mowat, Craig, Ng, Aylwin, Newman, William, Ophoff, Roel A, Papi, Laura, Palmieri, Orazio, Peyrin-Biroulet, Laurent, Panés, Julián, Phillips, Anne, Prescott, Natalie J., Proctor, Deborah D., Roberts, Rebecca, Russell, Richard, Rutgeerts, Paul, Sanderson, Jeremy, Sans, Miquel, Schumm, Philip, Seibold, Frank, Sharma, Yashoda, Simms, Lisa, Seielstad, Mark, Steinhart, A. Hillary, Targan, Stephan R., van den Berg, Leonard H., Vatn, Morten, Verspaget, Hein, Walters, Thomas, Wijmenga, Cisca, Wilson, David C., Westra, Harm-Jan, Xavier, Ramnik J., Zhao, Zhen Z., Ponsioen, Cyriel Y., Andersen, Vibeke, Torkvist, Leif, Gazouli, Maria, Anagnou, Nicholas P., Karlsen, Tom H., Kupcinskas, Limas, Sventoraityte, Jurgita, Mansfield, John C., Kugathasan, Subra, Silverberg, Mark S., Halfvarson, Jonas, Rotter, Jerome I., Mathew, Christopher G., Griffiths, Anne M., Gearry, Richard, Ahmad, Tariq, Brant, Steven R., Chamaillard, Mathias, Satsangi, Jack, Cho, Judy H., Schreiber, Stefan, Daly, Mark J., Barrett, Jeffrey C., Parkes, Miles, Annese, Vito, Hakonarson, Hakon, Radford-Smith, Graham, Duerr, Richard H., Vermeire, Séverine, Weersma, Rinse K., Rioux, John D.
Publicado em 2011

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

Por Sotoodehnia, Nona, Isaacs, Aaron, de Bakker, Paul I.W., Dörr, Marcus, Newton-Cheh, Christopher, Nolte, Ilja M., van der Harst, Pim, Müller, Martina, Eijgelsheim, Mark, Alonso, Alvaro, Hicks, Andrew A., Padmanabhan, Sandosh, Hayward, Caroline, Smith, Albert Vernon, Polasek, Ozren, Giovannone, Steven, Fu, Jingyuan, Magnani, Jared W., Marciante, Kristin D., Pfeufer, Arne, Gharib, Sina A., Teumer, Alexander, Li, Man, Bis, Joshua C., Rivadeneira, Fernando, Aspelund, Thor, Köttgen, Anna, Johnson, Toby, Rice, Kenneth, Sie, Mark P.S., Wang, Amanda Ying, Klopp, Norman, Fuchsberger, Christian, Wild, Sarah H., Leach, Irene Mateo, Estrada, Karol, Völker, Uwe, Wright, Alan F., Asselbergs, Folkert W., Qu, Jiaxiang, Chakravarti, Aravinda, Sinner, Moritz F., Kors, Jan A., Petersmann, Astrid, Harris, Tamara B., Soliman, Elsayed Z., Munroe, Patricia B., Psaty, Bruce M., Oostra, Ben A., Cupples, L. Adrienne, Perz, Siegfried, de Boer, Rudolf A., Uitterlinden, André G., Vözke, Henry, Spector, Timothy D., Liu, Fang-Yu, Boerwinkle, Eric, Dominiczak, Anna F., Rotter, Jerome I., van Herpen, Gé, Levy, Daniel, Wichmann, H.-Erich, van Gilst, Wiek H., Witteman, Jacqueline C.M., Kroemer, Heyo K., Kao, W.H. Linda, Heckbert, Susan R., Meitinger, Thomas, Hofman, Albert, Campbell, Harry, Folsom, Aaron R., van Veldhuisen, Dirk J., Schwienbacher, Christine, O’Donnell, Christopher J., Volpato, Claudia Beu, Caulfield, Mark J., Connell, John M., Launer, Lenore, Lu, Xiaowen, Franke, Lude, Fehrmann, Rudolf S.N., te Meerman, Gerard, Groen, Harry J.M., Weersma, Rinse K., van den Berg, Leonard H., Wijmenga, Cisca, Ophoff, Roel A., Navis, Gerjan, Rudan, Igor, Snieder, Harold, Wilson, James F., Pramstaller, Peter P., Siscovick, David S., Wang, Thomas J., Gudnason, Vilmundur, van Duijn, Cornelia M., Felix, Stephan B., Fishman, Glenn I., Jamshidi, Yalda, Stricker, Bruno H Ch, Samani, Nilesh J., Kääb, Stefan, Arking, Dan E.
Publicado em 2010