Unraveling the Regulatory Mechanisms Underlying Tissue-Dependent Genetic Variation of Gene Expression

It is known that genetic variants can affect gene expression, but it is not yet completely clear through what mechanisms genetic variation mediate this expression. We therefore compared the cis-effect of single nucleotide polymorphisms (SNPs) on gene expression between blood samples from 1,240 human...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fu, Jingyuan, Wolfs, Marcel G. M., Deelen, Patrick, Westra, Harm-Jan, Fehrmann, Rudolf S. N., te Meerman, Gerard J., Buurman, Wim A., Rensen, Sander S. M., Groen, Harry J. M., Weersma, Rinse K., van den Berg, Leonard H., Veldink, Jan, Ophoff, Roel A., Snieder, Harold, van Heel, David, Jansen, Ritsert C., Hofker, Marten H., Wijmenga, Cisca, Franke, Lude
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261927/
https://ncbi.nlm.nih.gov/pubmed/22275870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002431
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