Unraveling the Regulatory Mechanisms Underlying Tissue-Dependent Genetic Variation of Gene Expression

It is known that genetic variants can affect gene expression, but it is not yet completely clear through what mechanisms genetic variation mediate this expression. We therefore compared the cis-effect of single nucleotide polymorphisms (SNPs) on gene expression between blood samples from 1,240 human...

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Autori principali: Fu, Jingyuan, Wolfs, Marcel G. M., Deelen, Patrick, Westra, Harm-Jan, Fehrmann, Rudolf S. N., te Meerman, Gerard J., Buurman, Wim A., Rensen, Sander S. M., Groen, Harry J. M., Weersma, Rinse K., van den Berg, Leonard H., Veldink, Jan, Ophoff, Roel A., Snieder, Harold, van Heel, David, Jansen, Ritsert C., Hofker, Marten H., Wijmenga, Cisca, Franke, Lude
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261927/
https://ncbi.nlm.nih.gov/pubmed/22275870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002431
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