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A New Perspective on Transcriptional System Regulation (TSR): Towards TSR Profiling

It has been hypothesized that the net expression of a gene is determined by the combined effects of various transcriptional system regulators (TSRs). However, characterizing the complexity of regulation of the transcriptome is a major challenge. Principal component analysis on 17,550 heterogeneous h...

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Autors principals: Fehrmann, Rudolf S. N., de Jonge, Hendrik J. M., ter Elst, Arja, de Vries, André, Crijns, Anne G. P., Weidenaar, Alida C., Gerbens, Frans, de Jong, Steven, van der Zee, Ate G. J., de Vries, Elisabeth G. E., Kamps, Willem A., Hofstra, Robert M. W., te Meerman, Gerard J., de Bont, Eveline S. J. M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2250855/
https://ncbi.nlm.nih.gov/pubmed/18297136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001656
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