High Acute Myeloid Leukemia derived VEGFA levels are associated with a specific vascular morphology in the leukemic bone marrow

BACKGROUND: Acute Myeloid Leukemia (AML) bone marrow biopsies at diagnosis display enhanced angiogenesis and increased VEGFA expression. In a xenograft mouse model it was described that availability of free VEGFA versus bound VEGFA is related to different vascular morphology. In this study we invest...

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Main Authors: Weidenaar, Alida C., ter Elst, Arja, Koopmans-Klein, Gineke, Rosati, Stefano, den Dunnen, Wilfred F. A., Meeuwsen-de Boer, Tiny, Kamps, Willem A., Vellenga, Edo, de Bont, Eveline S. J. M.
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2011
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Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162634/
https://ncbi.nlm.nih.gov/pubmed/21468688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13402-011-0017-9
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