Exogenous HGF Bypasses the Effects of ErbB Inhibition on Tumor Cell Viability in Medulloblastoma Cell Lines

Recent clinical trials investigating receptor tyrosine kinase (RTK) inhibitors showed a limited clinical response in medulloblastoma. The present study investigated the role of micro-environmental growth factors expressed in the brain, such as HGF and EGF, in relation to the effects of hepatocyte gr...

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Veröffentlicht in:PLoS One
Hauptverfasser: Zomerman, Walderik W., Plasschaert, Sabine L. A., Diks, Sander H., Lourens, Harm-Jan, Meeuwsen-de Boer, Tiny, Hoving, Eelco W., den Dunnen, Wilfred F. A., de Bont, Eveline S. J. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619778/
https://ncbi.nlm.nih.gov/pubmed/26496080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141381
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