Improving accuracy of rare variant imputation with a two-step imputation approach

por Kreiner-Møller, Eskil, Medina-Gomez, Carolina, Uitterlinden, André G, Rivadeneira, Fernando, Estrada, Karol
Publicado en Eur J Hum Genet (2015)

GRIMP: a web- and grid-based tool for high-speed analysis of large-scale genome-wide association using imputed data

por Estrada, Karol, Abuseiris, Anis, Grosveld, Frank G., Uitterlinden, André G., Knoch, Tobias A., Rivadeneira, Fernando
Publicado 2009

Benchmarking machine learning models for late-onset alzheimer’s disease prediction from genomic data

por De Velasco Oriol, Javier, Vallejo, Edgar E., Estrada, Karol, Taméz Peña, José Gerardo, Disease Neuroimaging Initiative, The Alzheimer’s
Publicado en BMC Bioinformatics (2019)

Association between bone mineral density and type 2 diabetes mellitus: a meta-analysis of observational studies

por Ma, Lili, Oei, Ling, Jiang, Lindi, Estrada, Karol, Chen, Huiyong, Wang, Zhen, Yu, Qiang, Zillikens, Maria Carola, Gao, Xin, Rivadeneira, Fernando
Publicado 2012

Large common deletions associate with mortality at old age

por Kuningas, Maris, Estrada, Karol, Hsu, Yi-Hsiang, Nandakumar, Kannabiran, Uitterlinden, André G., Lunetta, Kathryn L., van Duijn, Cornelia M., Karasik, David, Hofman, Albert, Murabito, Joanne, Rivadeneira, Fernando, Kiel, Douglas P., Tiemeier, Henning
Publicado 2011

Challenges in conducting genome-wide association studies in highly admixed multi-ethnic populations: the Generation R Study

por Medina-Gomez, Carolina, Felix, Janine Frédérique, Estrada, Karol, Peters, Marjoline Josephine, Herrera, Lizbeth, Kruithof, Claudia Jeanette, Duijts, Liesbeth, Hofman, Albert, van Duijn, Cornelia Marja, Uitterlinden, Andreas Gerardus, Jaddoe, Vincent Wilfred Vishal, Rivadeneira, Fernando
Publicado en Eur J Epidemiol (2015)

Genome-wide meta-analysis, fine-mapping, and integrative prioritization implicate new Alzheimer’s disease risk genes

por Schwartzentruber, Jeremy, Cooper, Sarah, Liu, Jimmy Z., Barrio-Hernandez, Inigo, Bello, Erica, Kumasaka, Natsuhiko, Young, Adam M. H., Franklin, Robin J. M., Johnson, Toby, Estrada, Karol, Gaffney, Daniel J., Beltrao, Pedro, Bassett, Andrew
Publicado en Nat Genet (2021)

Genome-Wide Association Study in an Admixed Case Series Reveals IL12A as a New Candidate in Behçet Disease

por Kappen, Jasper H., Medina-Gomez, Carolina, van Hagen, P. Martin, Stolk, Lisette, Estrada, Karol, Rivadeneira, Fernando, Uitterlinden, Andre G., Stanford, Miles R., Ben-Chetrit, Eldat, Wallace, Graham R., Soylu, Merih, van Laar, Jan A.M.
Publicado en PLoS One (2015)

BIN1 favors the spreading of Tau via extracellular vesicles

por Crotti, Andrea, Sait, Hameetha Rajamohamend, McAvoy, Kathleen M., Estrada, Karol, Ergun, Ayla, Szak, Suzanne, Marsh, Galina, Jandreski, Luke, Peterson, Michael, Reynolds, Taylor L., Dalkilic-Liddle, Isin, Cameron, Andrew, Cahir-McFarland, Ellen, Ransohoff, Richard M.
Publicado en Sci Rep (2019)

A Pilot Genome-Wide Association Study in Postmenopausal Mexican-Mestizo Women Implicates the RMND1/CCDC170 Locus Is Associated with Bone Mineral Density

por Villalobos-Comparán, Marisela, Jiménez-Ortega, Rogelio F., Estrada, Karol, Parra-Torres, Alma Y., González-Mercado, Anahí, Patiño, Nelly, Castillejos-López, Manuel, Quiterio, Manuel, Fernandez-López, Juan Carlos, Ibarra, Bertha, Romero-Hidalgo, Sandra, Salmerón, Jorge, Velázquez-Cruz, Rafael
Publicado en Int J Genomics (2017)

A whole-genome sequence study identifies genetic risk factors for neuromyelitis optica

por Estrada, Karol, Whelan, Christopher W., Zhao, Fengmei, Bronson, Paola, Handsaker, Robert E., Sun, Chao, Carulli, John P., Harris, Tim, Ransohoff, Richard M., McCarroll, Steven A., Day-Williams, Aaron G., Greenberg, Benjamin M., MacArthur, Daniel G.
Publicado en Nat Commun (2018)

Identifying therapeutic drug targets using bidirectional effect genes

por Estrada, Karol, Froelich, Steven, Wuster, Arthur, Bauer, Christopher R., Sterling, Teague, Clark, Wyatt T., Ru, Yuanbin, Trinidad, Marena, Nguyen, Hong Phuc, Luu, Amanda R., Wendt, Daniel J., Yogalingam, Gouri, Yu, Guoying Karen, LeBowitz, Jonathan H., Cardon, Lon R.
Publicado en Nat Commun (2021)

Tissue Effect on Genetic Control of Transcript Isoform Variation

por Kwan, Tony, Grundberg, Elin, Koka, Vonda, Ge, Bing, Lam, Kevin C. L., Dias, Christel, Kindmark, Andreas, Mallmin, Hans, Ljunggren, Östen, Rivadeneira, Fernando, Estrada, Karol, van Meurs, Joyce B., Uitterlinden, Andre, Karlsson, Magnus, Ohlsson, Claes, Mellström, Dan, Nilsson, Olle, Pastinen, Tomi, Majewski, Jacek
Publicado 2009

Harnessing peripheral DNA methylation differences in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease

por Vasanthakumar, Aparna, Davis, Justin W., Idler, Kenneth, Waring, Jeffrey F., Asque, Elizabeth, Riley-Gillis, Bridget, Grosskurth, Shaun, Srivastava, Gyan, Kim, Sungeun, Nho, Kwangsik, Nudelman, Kelly N. H., Faber, Kelley, Sun, Yu, Foroud, Tatiana M., Estrada, Karol, Apostolova, Liana G., Li, Qingqin S., Saykin, Andrew J.
Publicado en Clin Epigenetics (2020)

Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome

por Baird, Denis A., Liu, Jimmy Z., Zheng, Jie, Sieberts, Solveig K., Perumal, Thanneer, Elsworth, Benjamin, Richardson, Tom G., Chen, Chia-Yen, Carrasquillo, Minerva M., Allen, Mariet, Reddy, Joseph S., De Jager, Philip L., Ertekin-Taner, Nilufer, Mangravite, Lara M., Logsdon, Ben, Estrada, Karol, Haycock, Philip C., Hemani, Gibran, Runz, Heiko, Smith, George Davey, Gaunt, Tom R.
Publicado en PLoS Genet (2021)

Population genomics in a disease targeted primary cell model

por Grundberg, Elin, Kwan, Tony, Ge, Bing, Lam, Kevin C.L., Koka, Vonda, Kindmark, Andreas, Mallmin, Hans, Dias, Joana, Verlaan, Dominique J., Ouimet, Manon, Sinnett, Daniel, Rivadeneira, Fernando, Estrada, Karol, Hofman, Albert, van Meurs, Joyce M., Uitterlinden, André, Beaulieu, Patrick, Graziani, Alexandru, Harmsen, Eef, Ljunggren, Östen, Ohlsson, Claes, Mellström, Dan, Karlsson, Magnus K., Nilsson, Olle, Pastinen, Tomi
Publicado 2009

Genomic inflation factors under polygenic inheritance

por Yang, Jian, Weedon, Michael N, Purcell, Shaun, Lettre, Guillaume, Estrada, Karol, Willer, Cristen J, Smith, Albert V, Ingelsson, Erik, O'Connell, Jeffrey R, Mangino, Massimo, Mägi, Reedik, Madden, Pamela A, Heath, Andrew C, Nyholt, Dale R, Martin, Nicholas G, Montgomery, Grant W, Frayling, Timothy M, Hirschhorn, Joel N, McCarthy, Mark I, Goddard, Michael E, Visscher, Peter M
Publicado 2011

Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research...

por Hsu, Yi-Hsiang, Li, Guo, Liu, Ching-Ti, Brody, Jennifer A., Karasik, David, Chou, Wen-Chi, Demissie, Serkalem, Nandakumar, Kannabiran, Zhou, Yanhua, Cheng, Chia-Ho, Gill, Richard, Gibbs, Richard A., Muzny, Donna, Santibanez, Jireh, Estrada, Karol, Rivadeneira, Fernando, Harris, Tamara, Gudnason, Vilmundur, Uitterlinden, Andre, Psaty, Bruce M, Robbins, John A., Adrienne Cupples, L, Kiel, Douglas P.
Publicado en Hum Mol Genet (2016)

High Bone Mineral Density and Fracture Risk in Type 2 Diabetes as Skeletal Complications of Inadequate Glucose Control: The Rotterdam Study

por Oei, Ling, Zillikens, M. Carola, Dehghan, Abbas, Buitendijk, Gabriëlle H.S., Castaño-Betancourt, Martha C., Estrada, Karol, Stolk, Lisette, Oei, Edwin H.G., van Meurs, Joyce B.J., Janssen, Joseph A.M.J.L., Hofman, Albert, van Leeuwen, Johannes P.T.M., Witteman, Jacqueline C.M., Pols, Huibert A.P., Uitterlinden, André G., Klaver, Caroline C.W., Franco, Oscar H., Rivadeneira, Fernando
Publicado 2013

Common variants at ten loci influence myocardial repolarization: the QTGEN consortium

por Newton-Cheh, Christopher, Eijgelsheim, Mark, Rice, Kenneth, de Bakker, Paul I. W., Yin, Xiaoyan, Estrada, Karol, Bis, Joshua, Marciante, Kristin, Rivadeneira, Fernando, Noseworthy, Peter A., Sotoodehnia, Nona, Smith, Nicholas L., Rotter, Jerome I., Kors, Jan A., Witteman, Jacqueline C.M., Hofman, Albert, Heckbert, Susan R., O’Donnell, Christopher J., Uitterlinden, Andre G., Psaty, Bruce M., Lumley, Thomas, Larson, Martin G., Stricker, Bruno H.Ch.
Publicado 2009