BIN1 favors the spreading of Tau via extracellular vesicles

Despite Bridging INtegrator 1 (BIN1) being the second most statistically-significant locus associated to Late Onset Alzheimer’s Disease, its role in disease pathogenesis remains to be clarified. As reports suggest a link between BIN1, Tau and extracellular vesicles, we investigated whether BIN1 coul...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Crotti, Andrea, Sait, Hameetha Rajamohamend, McAvoy, Kathleen M., Estrada, Karol, Ergun, Ayla, Szak, Suzanne, Marsh, Galina, Jandreski, Luke, Peterson, Michael, Reynolds, Taylor L., Dalkilic-Liddle, Isin, Cameron, Andrew, Cahir-McFarland, Ellen, Ransohoff, Richard M.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6603165/
https://ncbi.nlm.nih.gov/pubmed/31263146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45676-0
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