טוען...
Cell-autonomous and non-cell autonomous effects of neuronal BIN1 loss in vivo
BIN1 is the most important risk locus for Late Onset Alzheimer’s Disease (LOAD), after ApoE. BIN1 AD-associated SNPs correlate with Tau deposition as well as with brain atrophy. Furthermore, the level of neuronal-specific BIN1 isoform 1 protein is decreased in sporadic AD cases in parallel with neur...
שמור ב:
| הוצא לאור ב: | PLoS One |
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| Main Authors: | , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6692034/ https://ncbi.nlm.nih.gov/pubmed/31408457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220125 |
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