Capturing functional epigenomes for insight into metabolic diseases

door Allum, Fiona, Grundberg, Elin
Gepubliceerd in Mol Metab (2020)

Antibody responses boosted in seropositive healthcare workers after single dose of SARS-CoV-2 mRNA vaccine

door Bradley, Todd, Grundberg, Elin, Selvarangan, Rangaraj
Gepubliceerd in medRxiv (2021)

AKR1C2 and AKR1C3 expression in adipose tissue: Association with body fat distribution and regulatory variants

door Ostinelli, Giada, Vijay, Jinchu, Vohl, Marie-Claude, Grundberg, Elin, Tchernof, Andre
Gepubliceerd in Mol Cell Endocrinol (2021)

High-resolution epigenome analysis in nasal samples derived from children with respiratory viral infections reveals striking changes upon SARS-CoV-2 infection

door Winkley, Konner, Koseva, Boryana, Banerjee, Dithi, Cheung, Warren, Selvarangan, Rangaraj, Pastinen, Tomi, Grundberg, Elin
Gepubliceerd in medRxiv (2021)

Global miRNA expression and correlation with mRNA levels in primary human bone cells

door Laxman, Navya, Rubin, Carl-Johan, Mallmin, Hans, Nilsson, Olle, Pastinen, Tomi, Grundberg, Elin, Kindmark, Andreas
Gepubliceerd in RNA (2015)

UCP1 expression–associated gene signatures of human epicardial adipose tissue

door Chechi, Kanta, Vijay, Jinchu, Voisine, Pierre, Mathieu, Patrick, Bossé, Yohan, Tchernof, Andre, Grundberg, Elin, Richard, Denis
Gepubliceerd in JCI Insight (2019)

Genetic risk factors for decreased bone mineral accretion in children with asthma receiving multiple oral corticosteroid bursts

door Park, Heung-Woo, Ge, Bing, Tse, Szeman, Grundberg, Elin, Pastinen, Tomi, Kelly, H. William, Tantisira, Kelan G.
Gepubliceerd in J Allergy Clin Immunol (2015)

Humoral immune responses during SARS-CoV-2 mRNA vaccine administration in seropositive and seronegative individuals

door Fraley, Elizabeth, LeMaster, Cas, Geanes, Eric, Banerjee, Dithi, Khanal, Santosh, Grundberg, Elin, Selvarangan, Rangaraj, Bradley, Todd
Gepubliceerd in BMC Med (2021)

A Comparison of the Whole Genome Approach of MeDIP-Seq to the Targeted Approach of the Infinium HumanMethylation450 BeadChip(®) for Methylome Profiling

door Clark, Christine, Palta, Priit, Joyce, Christopher J., Scott, Carol, Grundberg, Elin, Deloukas, Panos, Palotie, Aarno, Coffey, Alison J.
Gepubliceerd in 2012

Antibody Responses after a Single Dose of SARS-CoV-2 mRNA Vaccine

door Bradley, Todd, Grundberg, Elin, Selvarangan, Rangaraj, LeMaster, Cas, Fraley, Elizabeth, Banerjee, Dithi, Belden, Bradley, Louiselle, Daniel, Nolte, Nick, Biswell, Rebecca, Pastinen, Tomi, Myers, Angela, Schuster, Jennifer
Gepubliceerd in N Engl J Med (2021)

Dominant gut Prevotella copri in gastrectomised non-obese diabetic Goto–Kakizaki rats improves glucose homeostasis through enhanced FXR signalling

door Péan, Noémie, Le Lay, Aurelie, Brial, Francois, Wasserscheid, Jessica, Rouch, Claude, Vincent, Mylène, Myridakis, Antonis, Hedjazi, Lyamine, Dumas, Marc-Emmanuel, Grundberg, Elin, Lathrop, Mark, Magnan, Christophe, Dewar, Ken, Gauguier, Dominique
Gepubliceerd in Diabetologia (2020)

Global Analysis of the Impact of Environmental Perturbation on cis-Regulation of Gene Expression

door Grundberg, Elin, Adoue, Veronique, Kwan, Tony, Ge, Bing, Duan, Qing Ling, Lam, Kevin C. L., Koka, Vonda, Kindmark, Andreas, Weiss, Scott T., Tantisira, Kelan, Mallmin, Hans, Raby, Benjamin A., Nilsson, Olle, Pastinen, Tomi
Gepubliceerd in 2011

Targeted screening of cis-regulatory variation in human haplotypes

door Verlaan, Dominique J., Ge, Bing, Grundberg, Elin, Hoberman, Rose, Lam, Kevin C.L., Koka, Vonda, Dias, Joana, Gurd, Scott, Martin, Nicolas W., Mallmin, Hans, Nilsson, Olof, Harmsen, Eef, Dewar, Ken, Kwan, Tony, Pastinen, Tomi
Gepubliceerd in 2009

The Presence of Methylation Quantitative Trait Loci Indicates a Direct Genetic Influence on the Level of DNA Methylation in Adipose Tissue

door Drong, Alexander W., Nicholson, George, Hedman, Åsa K., Meduri, Eshwar, Grundberg, Elin, Small, Kerrin S., Shin, So-Youn, Bell, Jordana T., Karpe, Fredrik, Soranzo, Nicole, Spector, Tim D., McCarthy, Mark I., Deloukas, Panos, Rantalainen, Mattias, Lindgren, Cecilia M.
Gepubliceerd in 2013

Higher chylomicron remnants and LDL particle numbers associate with CD36 SNPs and DNA methylation sites that reduce CD36

door Love-Gregory, Latisha, Kraja, Aldi T., Allum, Fiona, Aslibekyan, Stella, Hedman, Åsa K., Duan, Yanan, Borecki, Ingrid B., Arnett, Donna K., McCarthy, Mark I., Deloukas, Panos, Ordovas, Jose M., Hopkins, Paul N., Grundberg, Elin, Abumrad, Nada A.
Gepubliceerd in J Lipid Res (2016)

ASCL2 reciprocally controls key trophoblast lineage decisions during hemochorial placenta development

door Varberg, Kaela M., Iqbal, Khursheed, Muto, Masanaga, Simon, Mikaela E., Scott, Regan L., Kozai, Keisuke, Choudhury, Ruhul H., Aplin, John D., Biswell, Rebecca, Gibson, Margaret, Okae, Hiroaki, Arima, Takahiro, Vivian, Jay L., Grundberg, Elin, Soares, Michael J.
Gepubliceerd in Proc Natl Acad Sci U S A (2021)

Customized MethylC-Capture Sequencing to Evaluate Variation in the Human Sperm DNA Methylome Representative of Altered Folate Metabolism

door Chan, Donovan, Shao, Xiaojian, Dumargne, Marie-Charlotte, Aarabi, Mahmoud, Simon, Marie-Michelle, Kwan, Tony, Bailey, Janice L., Robaire, Bernard, Kimmins, Sarah, San Gabriel, Maria C., Zini, Armand, Librach, Clifford, Moskovtsev, Sergey, Grundberg, Elin, Bourque, Guillaume, Pastinen, Tomi, Trasler, Jacquetta M.
Gepubliceerd in Environ Health Perspect (2019)

Tissue Effect on Genetic Control of Transcript Isoform Variation

door Kwan, Tony, Grundberg, Elin, Koka, Vonda, Ge, Bing, Lam, Kevin C. L., Dias, Christel, Kindmark, Andreas, Mallmin, Hans, Ljunggren, Östen, Rivadeneira, Fernando, Estrada, Karol, van Meurs, Joyce B., Uitterlinden, Andre, Karlsson, Magnus, Ohlsson, Claes, Mellström, Dan, Nilsson, Olle, Pastinen, Tomi, Majewski, Jacek
Gepubliceerd in 2009

Identification of an imprinted master trans-regulator at the KLF14 locus related to multiple metabolic phenotypes

door Small, Kerrin S., Hedman, Åsa K., Grundberg, Elin, Nica, Alexandra C., Thorleifsson, Gudmar, Kong, Augustine, Thorsteindottir, Unnur, Shin, So-Youn, Richards, Hannah B., Soranzo, Nicole, Ahmadi, Kourosh R., Lindgren, Cecilia M., Stefansson, Kari, Dermitzakis, Emmanouil T., Deloukas, Panos, Spector, Timothy D., McCarthy, Mark I.
Gepubliceerd in 2011

Population whole-genome bisulfite sequencing across two tissues highlights the environment as the principal source of human methylome variation

door Busche, Stephan, Shao, Xiaojian, Caron, Maxime, Kwan, Tony, Allum, Fiona, Cheung, Warren A., Ge, Bing, Westfall, Susan, Simon, Marie-Michelle, Barrett, Amy, Bell, Jordana T., McCarthy, Mark I., Deloukas, Panos, Blanchette, Mathieu, Bourque, Guillaume, Spector, Timothy D., Lathrop, Mark, Pastinen, Tomi, Grundberg, Elin
Gepubliceerd in Genome Biol (2015)