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A Comparison of the Whole Genome Approach of MeDIP-Seq to the Targeted Approach of the Infinium HumanMethylation450 BeadChip(®) for Methylome Profiling

DNA methylation is one of the most studied epigenetic marks in the human genome, with the result that the desire to map the human methylome has driven the development of several methods to map DNA methylation on a genomic scale. Our study presents the first comparison of two of these techniques - th...

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Главные авторы: Clark, Christine, Palta, Priit, Joyce, Christopher J., Scott, Carol, Grundberg, Elin, Deloukas, Panos, Palotie, Aarno, Coffey, Alison J.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510246/
https://ncbi.nlm.nih.gov/pubmed/23209683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050233
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