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A Comparison of the Whole Genome Approach of MeDIP-Seq to the Targeted Approach of the Infinium HumanMethylation450 BeadChip(®) for Methylome Profiling

DNA methylation is one of the most studied epigenetic marks in the human genome, with the result that the desire to map the human methylome has driven the development of several methods to map DNA methylation on a genomic scale. Our study presents the first comparison of two of these techniques - th...

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Autores principales: Clark, Christine, Palta, Priit, Joyce, Christopher J., Scott, Carol, Grundberg, Elin, Deloukas, Panos, Palotie, Aarno, Coffey, Alison J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510246/
https://ncbi.nlm.nih.gov/pubmed/23209683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050233
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