ASCL2 reciprocally controls key trophoblast lineage decisions during hemochorial placenta development

Invasive trophoblast cells are critical to spiral artery remodeling in hemochorial placentation. Insufficient trophoblast cell invasion and vascular remodeling can lead to pregnancy disorders including preeclampsia, preterm birth, and intrauterine growth restriction. Previous studies in mice identif...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Varberg, Kaela M., Iqbal, Khursheed, Muto, Masanaga, Simon, Mikaela E., Scott, Regan L., Kozai, Keisuke, Choudhury, Ruhul H., Aplin, John D., Biswell, Rebecca, Gibson, Margaret, Okae, Hiroaki, Arima, Takahiro, Vivian, Jay L., Grundberg, Elin, Soares, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7958375/
https://ncbi.nlm.nih.gov/pubmed/33649217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2016517118
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