Large common deletions associate with mortality at old age

Copy-number variants (CNVs) are a source of genetic variation that increasingly are associated with human disease. However, the role of CNVs in human lifespan is to date unknown. To identify CNVs that influence mortality at old age, we analyzed genome-wide CNV data in 5178 participants of Rotterdam...

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Detalhes bibliográficos
Main Authors: Kuningas, Maris, Estrada, Karol, Hsu, Yi-Hsiang, Nandakumar, Kannabiran, Uitterlinden, André G., Lunetta, Kathryn L., van Duijn, Cornelia M., Karasik, David, Hofman, Albert, Murabito, Joanne, Rivadeneira, Fernando, Kiel, Douglas P., Tiemeier, Henning
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Association Studies Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188993/
https://ncbi.nlm.nih.gov/pubmed/21835882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr340
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