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Improving accuracy of rare variant imputation with a two-step imputation approach
Genotype imputation has been the pillar of the success of genome-wide association studies (GWAS) for identifying common variants associated with common diseases. However, most GWAS have been run using only 60 HapMap samples as reference for imputation, meaning less frequent and rare variants not bei...
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| Publicado no: | Eur J Hum Genet |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4326719/ https://ncbi.nlm.nih.gov/pubmed/24939589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2014.91 |
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