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Regulators of homologous recombination repair as novel targets for cancer treatment

To cope with DNA damage, cells possess a complex signaling network called the ‘DNA damage response’, which coordinates cell cycle control with DNA repair. The importance of this network is underscored by the cancer predisposition that frequently goes along with hereditary mutations in DNA repair gen...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Krajewska, Małgorzata, Fehrmann, Rudolf S. N., de Vries, Elisabeth G. E., van Vugt, Marcel A. T. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367534/
https://ncbi.nlm.nih.gov/pubmed/25852742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00096
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