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Regulators of homologous recombination repair as novel targets for cancer treatment

To cope with DNA damage, cells possess a complex signaling network called the ‘DNA damage response’, which coordinates cell cycle control with DNA repair. The importance of this network is underscored by the cancer predisposition that frequently goes along with hereditary mutations in DNA repair gen...

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Podrobná bibliografie
Vydáno v:Front Genet
Hlavní autoři: Krajewska, Małgorzata, Fehrmann, Rudolf S. N., de Vries, Elisabeth G. E., van Vugt, Marcel A. T. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367534/
https://ncbi.nlm.nih.gov/pubmed/25852742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00096
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