A case-only study of gene-environment interaction between genetic susceptibility variants in NOD2 and cigarette smoking in Crohn's disease aetiology

Por Helbig, Katherine L, Nothnagel, Michael, Hampe, Jochen, Balschun, Tobias, Nikolaus, Susanna, Schreiber, Stefan, Franke, Andre, Nöthlings, Ute
Publicado em 2012

The age related markers lipofuscin and apoptosis show different genetic architecture by QTL mapping in short-lived Nothobranchius fish

Por Ng'oma, Enoch, Reichwald, Kathrin, Dorn, Alexander, Wittig, Michael, Balschun, Tobias, Franke, Andre, Platzer, Matthias, Cellerino, Allesandro
Publicado em 2014

Assessment of heterogeneity between European Populations: a Baltic and Danish replication case-control study of SNPs from a recent European ulcerative colitis genome wide associati...

Por Andersen, Vibeke, Ernst, Anja, Sventoraityte, Jurgita, Kupcinskas, Limas, Jacobsen, Bent A, Krarup, Henrik B, Vogel, Ulla, Jonaitis, Laimas, Denapiene, Goda, Kiudelis, Gediminas, Balschun, Tobias, Franke, Andre
Publicado em 2011

PTGER4 Expression-Modulating Polymorphisms in the 5p13.1 Region Predispose to Crohn's Disease and Affect NF-κB and XBP1 Binding Sites

Por Glas, Jürgen, Seiderer, Julia, Czamara, Darina, Pasciuto, Giulia, Diegelmann, Julia, Wetzke, Martin, Olszak, Torsten, Wolf, Christiane, Müller-Myhsok, Bertram, Balschun, Tobias, Achkar, Jean-Paul, Kamboh, M. Ilyas, Franke, Andre, Duerr, Richard H., Brand, Stephan
Publicado em 2012

Systematic Association Mapping Identifies NELL1 as a Novel IBD Disease Gene

Por Franke, Andre, Hampe, Jochen, Rosenstiel, Philip, Becker, Christian, Wagner, Florian, Häsler, Robert, Little, Randall D., Huse, Klaus, Ruether, Andreas, Balschun, Tobias, Wittig, Michael, ElSharawy, Abdou, Mayr, Gabriele, Albrecht, Mario, Prescott, Natalie J., Onnie, Clive M., Fournier, Hélène, Keith, Tim, Radelof, Uwe, Platzer, Matthias, Mathew, Christopher G., Stoll, Monika, Krawczak, Michael, Nürnberg, Peter, Schreiber, Stefan
Publicado em 2007

Combined Analysis of Genome-wide Association Studies for Crohn Disease and Psoriasis Identifies Seven Shared Susceptibility Loci

Por Ellinghaus, David, Ellinghaus, Eva, Nair, Rajan P., Stuart, Philip E., Esko, Tõnu, Metspalu, Andres, Debrus, Sophie, Raelson, John V., Tejasvi, Trilokraj, Belouchi, Majid, West, Sarah L., Barker, Jonathan N., Kõks, Sulev, Kingo, Külli, Balschun, Tobias, Palmieri, Orazio, Annese, Vito, Gieger, Christian, Wichmann, H. Erich, Kabesch, Michael, Trembath, Richard C., Mathew, Christopher G., Abecasis, Gonçalo R., Weidinger, Stephan, Nikolaus, Susanna, Schreiber, Stefan, Elder, James T., Weichenthal, Michael, Nothnagel, Michael, Franke, Andre
Publicado em 2012

Mutational Characterization of the Bile Acid Receptor TGR5 in Primary Sclerosing Cholangitis

Por Hov, Johannes R., Keitel, Verena, Laerdahl, Jon K., Spomer, Lina, Ellinghaus, Eva, ElSharawy, Abdou, Melum, Espen, Boberg, Kirsten M., Manke, Thomas, Balschun, Tobias, Schramm, Christoph, Bergquist, Annika, Weismüller, Tobias, Gotthardt, Daniel, Rust, Christian, Henckaerts, Liesbet, Onnie, Clive M., Weersma, Rinse K., Sterneck, Martina, Teufel, Andreas, Runz, Heiko, Stiehl, Adolf, Ponsioen, Cyriel Y., Wijmenga, Cisca, Vatn, Morten H., Stokkers, Pieter C. F., Vermeire, Severine, Mathew, Christopher G., Lie, Benedicte A., Beuers, Ulrich, Manns, Michael P., Schreiber, Stefan, Schrumpf, Erik, Häussinger, Dieter, Franke, Andre, Karlsen, Tom H.
Publicado em 2010

Immunochip analyses identify a novel risk locus for primary biliary cirrhosis at 13q14, multiple independent associations at four established risk loci and epistasis between 1p31 a...

Por Juran, Brian D., Hirschfield, Gideon M., Invernizzi, Pietro, Atkinson, Elizabeth J., Li, Yafang, Xie, Gang, Kosoy, Roman, Ransom, Michael, Sun, Ye, Bianchi, Ilaria, Schlicht, Erik M., Lleo, Ana, Coltescu, Catalina, Bernuzzi, Francesca, Podda, Mauro, Lammert, Craig, Shigeta, Russell, Chan, Landon L., Balschun, Tobias, Marconi, Maurizio, Cusi, Daniele, Heathcote, E. Jenny, Mason, Andrew L., Myers, Robert P., Milkiewicz, Piotr, Odin, Joseph A., Luketic, Velimir A., Bacon, Bruce R., Bodenheimer, Henry C., Liakina, Valentina, Vincent, Catherine, Levy, Cynthia, Franke, Andre, Gregersen, Peter K., Bossa, Fabrizio, Gershwin, M. Eric, deAndrade, Mariza, Amos, Christopher I., Lazaridis, Konstantinos N., Seldin, Michael F., Siminovitch, Katherine A.
Publicado em 2012

Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci

Por Melum, Espen, Franke, Andre, Schramm, Christoph, Weismüller, Tobias J, Gotthardt, Daniel Nils, Offner, Felix A, Juran, Brian D, Laerdahl, Jon K, Labi, Verena, Björnsson, Einar, Weersma, Rinse K, Henckaerts, Liesbet, Teufel, Andreas, Rust, Christian, Ellinghaus, Eva, Balschun, Tobias, Boberg, Kirsten Muri, Ellinghaus, David, Bergquist, Annika, Sauer, Peter, Ryu, Euijung, Hov, Johannes Roksund, Wedemeyer, Jochen, Lindkvist, Björn, Wittig, Michael, Porte, Robert J, Holm, Kristian, Gieger, Christian, Wichmann, H-Erich, Stokkers, Pieter, Ponsioen, Cyriel Y, Runz, Heiko, Stiehl, Adolf, Wijmenga, Cisca, Sterneck, Martina, Vermeire, Severine, Beuers, Ulrich, Villunger, Andreas, Schrumpf, Erik, Lazaridis, Konstantinos N, Manns, Michael P, Schreiber, Stefan, Karlsen, Tom H
Publicado no Nat Genet (2010)

Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

Por Hunt, Karen A, Smyth, Deborah J, Balschun, Tobias, Ban, Maria, Mistry, Vanisha, Ahmed, Tariq, Anand, Vidya, Barrett, Jeffrey C, Bhaw-Rosun, Leena, Bockett, Nicholas A, Brand, Oliver J, Brouwer, Elisabeth, Concannon, Patrick, Cooper, Jason D, Dias, Kerith-Rae M, van Diemen, Cleo C, Dubois, Patrick C, Edkins, Sarah, Fölster-Holst, Regina, Fransen, Karin, Glass, David N., Heap, Graham AR, Hofmann, Sylvia, Huizinga, Tom WJ, Hunt, Sarah, Langford, Cordelia, Lee, James, Mansfield, John, Marrosu, Maria Giovanna, Mathew, Christopher G, Mein, Charles A, Müller-Quernheim, Joachim, Nutland, Sarah, Onengut-Gumuscu, Suna, Ouwehand, Willem, Pearce, Kerra, Prescott, Natalie, Posthumus, Marcel D, Potter, Simon, Rosati, Giulio, Sambrook, Jennifer, Satsangi, Jack, Schreiber, Stefan, Shtir, Corina, Simmonds, Matthew J, Sudman, Marc, Thompson, Susan D, Toes, Rene, Trynka, Gosia, Vyse, Timothy J, Walker, Neil M, Weidinger, Stephan, Zhernakova, Alexandra, Zoledziewska, Magdalena, Weersma, Rinse K, Gough, Stephen CL, Sawcer, Stephen, Wijmenga, Cisca, Parkes, Miles, Cucca, Francesco, Franke, Andre, Deloukas, Panos, Rich, Stephen S., Todd, John A, van Heel, David A
Publicado em 2011

Meta-Analysis Increases to 71 the Tally of Confirmed Crohn’s Disease Susceptibility Loci

Por Franke, Andre, McGovern, Dermot P.B., Barrett, Jeffrey C., Wang, Kai, Radford-Smith, Graham L., Ahmad, Tariq, Lees, Charlie W., Balschun, Tobias, Lee, James, Roberts, Rebecca, Anderson, Carl A., Bis, Joshua C., Bumpstead, Suzanne, Ellinghaus, David, Festen, Eleonora M., Georges, Michel, Haritunians, Talin, Jostins, Luke, Latiano, Anna, Mathew, Christopher G., Montgomery, Grant W., Prescott, Natalie J., Rotter, Jerome I., Schumm, Philip, Sharma, Yashoda, Simms, Lisa A., Taylor, Kent D., Whiteman, David, Wijmenga, Cisca, Baldassano, Robert N., Barclay, Murray, Bayless, Theodore M., Brand, Stephan, Buning, Carsten, Cohen, Albert, Colombel, Jean-Frederick, Cottone, Mario, Stronati, Laura, Denson, Ted, De Vos, Martine, D’Inca, Renata, Dubinsky, Marla, Edwards, Cathryn, Florin, Tim, Franchimont, Denis, Gearry, Richard, Glas, Jürgen, Van Gossum, Andre, Guthery, Stephen L., Halfvarson, Jonas, Hommes, Daan, Hugot, Jean-Pierre, Laukens, Debby, Lawrance, Ian, Lemann, Marc, Levine, Arie, Libioulle, Cecile, Louis, Edouard, Mowat, Craig, Newman, William, Panés, Julián, Phillips, Anne, Proctor, Deborah D., Regueiro, Miguel, Rutgeerts, Paul, Sanderson, Jeremy, Sans, Miquel, Seibold, Frank, Steinhart, A. Hillary, Stokkers, Pieter C.F., Torkvist, Leif, Ublick, Gerd Kullak, Raychaudhuri, Soumya, Green, Todd, Walters, Thomas, Targan, Stephan R., Brant, Steven R., Rioux, John D., D’Amato, Mauro, Weersma, Rinse, Kugathasan, Subra, Griffiths, Anne M., Mansfield, John C., Vermeire, Severine, Duerr, Richard H., Silverberg, Mark S., Satsangi, Jack, Schreiber, Stefan, Cho, Judy H., Annese, Vito, Hakonarson, Hakon, Daly, Mark J., Parkes, Miles
Publicado em 2010

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

Por Jostins, Luke, Ripke, Stephan, Weersma, Rinse K, Duerr, Richard H, McGovern, Dermot P, Hui, Ken Y, Lee, James C, Schumm, L Philip, Sharma, Yashoda, Anderson, Carl A, Essers, Jonah, Mitrovic, Mitja, Ning, Kaida, Cleynen, Isabelle, Theatre, Emilie, Spain, Sarah L, Raychaudhuri, Soumya, Goyette, Philippe, Wei, Zhi, Abraham, Clara, Achkar, Jean-Paul, Ahmad, Tariq, Amininejad, Leila, Ananthakrishnan, Ashwin N, Andersen, Vibeke, Andrews, Jane M, Baidoo, Leonard, Balschun, Tobias, Bampton, Peter A, Bitton, Alain, Boucher, Gabrielle, Brand, Stephan, Büning, Carsten, Cohain, Ariella, Cichon, Sven, D’Amato, Mauro, De Jong, Dirk, Devaney, Kathy L, Dubinsky, Marla, Edwards, Cathryn, Ellinghaus, David, Ferguson, Lynnette R, Franchimont, Denis, Fransen, Karin, Gearry, Richard, Georges, Michel, Gieger, Christian, Glas, Jürgen, Haritunians, Talin, Hart, Ailsa, Hawkey, Chris, Hedl, Matija, Hu, Xinli, Karlsen, Tom H, Kupcinskas, Limas, Kugathasan, Subra, Latiano, Anna, Laukens, Debby, Lawrance, Ian C, Lees, Charlie W, Louis, Edouard, Mahy, Gillian, Mansfield, John, Morgan, Angharad R, Mowat, Craig, Newman, William, Palmieri, Orazio, Ponsioen, Cyriel Y, Potocnik, Uros, Prescott, Natalie J, Regueiro, Miguel, Rotter, Jerome I, Russell, Richard K, Sanderson, Jeremy D, Sans, Miquel, Satsangi, Jack, Schreiber, Stefan, Simms, Lisa A, Sventoraityte, Jurgita, Targan, Stephan R, Taylor, Kent D, Tremelling, Mark, Verspaget, Hein W, De Vos, Martine, Wijmenga, Cisca, Wilson, David C, Winkelmann, Juliane, Xavier, Ramnik J, Zeissig, Sebastian, Zhang, Bin, Zhang, Clarence K, Zhao, Hongyu, Silverberg, Mark S, Annese, Vito, Hakonarson, Hakon, Brant, Steven R, Radford-Smith, Graham, Mathew, Christopher G, Rioux, John D, Schadt, Eric E, Daly, Mark J, Franke, Andre, Parkes, Miles, Vermeire, Severine, Barrett, Jeffrey C, Cho, Judy H
Publicado em 2012