Immunochip analyses identify a novel risk locus for primary biliary cirrhosis at 13q14, multiple independent associations at four established risk loci and epistasis between 1p31 and 7q32 risk variants

To further characterize the genetic basis of primary biliary cirrhosis (PBC), we genotyped 2426 PBC patients and 5731 unaffected controls from three independent cohorts using a single nucleotide polymorphism (SNP) array (Immunochip) enriched for autoimmune disease risk loci. Meta-analysis of the gen...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Juran, Brian D., Hirschfield, Gideon M., Invernizzi, Pietro, Atkinson, Elizabeth J., Li, Yafang, Xie, Gang, Kosoy, Roman, Ransom, Michael, Sun, Ye, Bianchi, Ilaria, Schlicht, Erik M., Lleo, Ana, Coltescu, Catalina, Bernuzzi, Francesca, Podda, Mauro, Lammert, Craig, Shigeta, Russell, Chan, Landon L., Balschun, Tobias, Marconi, Maurizio, Cusi, Daniele, Heathcote, E. Jenny, Mason, Andrew L., Myers, Robert P., Milkiewicz, Piotr, Odin, Joseph A., Luketic, Velimir A., Bacon, Bruce R., Bodenheimer, Henry C., Liakina, Valentina, Vincent, Catherine, Levy, Cynthia, Franke, Andre, Gregersen, Peter K., Bossa, Fabrizio, Gershwin, M. Eric, deAndrade, Mariza, Amos, Christopher I., Lazaridis, Konstantinos N., Seldin, Michael F., Siminovitch, Katherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Association Studies Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490520/
https://ncbi.nlm.nih.gov/pubmed/22936693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds359
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados